Long story, around 25 years ago I broke my ankle quite badly and dislocated it, they straightened it in A & E but the bones didn't knit together correctly. The Orthopaedic surgeon I seen said they re-break the joint and reset it, as I'd just bought a house I wasn't keen on being in plaster again so refused, the surgeon then went on to say I'd likely get arthritis in the joint by the time I was 30 and recommended taking a CLO supplement, he was a great believer in the benefits of CLO and took a supplement himself.
I never did get arthritis in the joint but was this down to the CLO supplement I cannot say, but I first took it in a capsule form and around 5 - 6 years ago started taking it off the spoon (10ml), it's also said to help with cholesterol levels to which I've never had a problem with.