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Becoming resistant to insulin?

keishamarie

Well-Known Member
Messages
113
Type of diabetes
Type 1
Treatment type
Insulin
Has anyone else found that they've possibly become resistant to some insulin?
For background - I'm a 27 year old Female have been diabetic type 1 for now nearly 15 years and always been on the same insulin (Nova Rapid & Lantus) I move my injection sites everything I do one from legs to stomach but recently I've found that no matter how much insulin I take I seem to only go up in numbers rather than down. I then drop to around 5 for an hour and then shoot back up to a ridiculous number. I'm getting highly frustrated with it and it's making me dread taking my sugars and feel like im just constantly injecting.

Any information/experiences would be lovely to hear!

Xo
 
Now ....... I'm not wanting to hijack your thread, so I'll try not to do that ! :-) I am in the process of putting some thoughts together about the very subject you're posting about - i.e. crazy blood sugar readings, totally out-of-control, and injection doses not seeming able to correct it the way it should. And I logged in to think about how best to start a thread, looking for help from all and any interested forum members.

And straight away, I noticed this new thread.

It's a weird subject matter, everyone will find it difficult to believe where I think the connection is, and I haven't yet got the final answer to it ........ I'm kind of in the right field, but still with a couple of large haystacks to look through ! Everyone will understand when I post, but can you give me a day or two to come back on this subject, I need time to put it together in the correct way, and I'm also a bit inundated right now.
But, I have been suffering the same weird situation for several years now (with erratic BS levels), and it's taken a long time to pin down where I think the answers are. I think it might also answer the real reason for what we understand of Liver Dump / Dawn Phenomenon / Foot-on-Floor syndrome.
What I'm hoping to get is forum members who can all add to this investigation, and between us all, we can finally pin this down, but I don't want to be asking too much just yet !!!
OK keishamarie, it's looking like I'm already hijacking your thread, and I didn't want to do that. When I post back in a couple of days, I'll decide whether to continue on here, or start afresh.
Based on my own experience on this, I would say you're probably not doing anything wrong at all, and there's probably nothing wrong with your injection site choices etc., so don't let it mess with your head. I was finger pricking like crazy at the beginning, and thankfully now have a CGM which has enabled me to slowly troubleshoot this problem. But I would say ........ if you're having to do a lot of extra injections, go careful, for obvious reasons.
Back soon as I can .......... I will try within 48 hours.
 
Hi @keishamarie and @James472
Its a pet subject of mine but i don't post about it because there is no explanation to it and @James472 i wish you well with your research.....

50th year a type 1 here.

I suffer with bouts of resistance from time to time but they only tend to last 12 to 18 hours.
I take more insulin eat less food and walk a lot and that combination helps but i still don't know why it happens.

I eat more on a sunday than any other day and am less active and do tend to struggle the following day even though i have kept my levels good on the sunday.

No scientific proof though.

Long live bacon butties and a sunday roast!!!

I take novorapid and levimir.

Please don't let it get you down @keishamarie just accept it and recognize it early and give my idea of more insulin less food and much walking and of course take care when it disappears and the pendulum of normality swings back at you......


I wish you well

Tony
 
Hi @keishamarie yes this has been a problem for me on and off for the last 10 years. Like @James472 I think the reasons are complex. Connected to previous weeks food/exercise/sleep patterns/stress and even the weather. For me the situation corrects for no reason and I have a period of calm again. Or as @ANTJE suggests I basal test and adjust.

Basal testing would be my first port of call. Without meaning to offend you, you are now well into your 20s and our bodies evolve as we age and our requirements for everything in our bodies evolve. Why not insulin.
My second suggestion would be a change of insulin. Lantus is an old basal. My team moved me about 7 years ago as they were stopping prescribing it and moving onto more modern up to date insulins. I am now on Tresiba which I love for its stability. Drawbacks being changes to doses take about 3 days to show. There are also faster boluses than NovoRapid about. Maybe time for you to try a change and mix things up a bit. Well done for managing well from childhood through adolescence. Not easy I am sure. There is nothing wrong with shaking things up a bit now. Maybe even a pump? Good luck!
 
Hi @keishamarie it is taking a bit longer to decide how best to do this, and time is something I don't have much of at the moment. But soon.
I decided best not to flood your thread, and also it might not apply in your case, your situation could be a different one. Plus, the team here have already put down some good suggestions for you to consider.

So I've started a separate thread over here - https://www.diabetes.co.uk/forum/threads/am-i-imagining-this.200052/

Good Luck, keep doing what you're doing, careful with the doses, and just keep monitoring the blood sugar levels as best you can. Don't let it get to you - we all just learn to live with the complications of diabetes. They can be a real pain at times, but that's when it's good to know there's a forum, and plenty of others that are going through similar things, and ready to offer help.

James
 
Has anyone else found that they've possibly become resistant to some insulin?
As a T2 I became somewhat resistant after a long course of 'hay fever 'desensitising injections and to overcome this I was prescribed pioglitazone tablets which do assist in keeping my HbA1c stable at 6.3%
 
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