ElyDave said:Deep sigh as i explain yet again that it's t1, and it's an autoimmune condition
mpe said:ElyDave said:Deep sigh as i explain yet again that it's t1, and it's an autoimmune condition
There are slim T2s (as well as obese T1s). Something like 1/5 of people diagnosed with T2 are not overweight anyway. There don't appear to be any figures for what proportion of the other 4/5 lose weight...
Depending on how fast a T1 loses beta cells (or beta cell functionality) there need not always be a "honeymoon period". (Or it can be long past by the time they get diagnosed.Andrea616570 said:The way it was explained to me, a type 1 diabetic (after what they used to call the "honeymoon period") makes NO INSULIN on their own. So it's a pretty safe bet that they must take insulin in one way or another, if they expect to live...
T2 involves insulin resistance. Which means that cells don't respond as they should to insulin. Thus a T2, even with impaired beta cell functionality, may be producing more insulin than a non diabetic. A strange quirk is that often fat cells do not become insulin resistant (or as insulin resistant) as other cells. Something which may have a lot to do with the association between T2 and obesity. Being unable to use most of the glucose in the diet for respiration it gets converted to fat. But a high blood glucose level, frequently topped up with dietary glucose, inhibits non glucose respiration. Only cells without mitochondria actually "need glucose". (Typically cells use glycolysis to produce pyruvic acid from glucose. The issue with the brain is that only sugars, ketones & alpha hydroxy acids can easily get into neurons.)That, by definition would be a safe way to distinguish type 1 from type 2. Type 2's are harder to nail down because SOME TIMES: they make a bit of insulin, can control with diet alone, need oral meds, don't make any insulin, need to take insulin...or all sorts of combinations of the above, as long an actual paradox is not created.
mpe said:T2 involves insulin resistance. Which means that cells don't respond as they should to insulin. Thus a T2, even with impaired beta cell functionality, may be producing more insulin than a non diabetic.
Thundercat said:It's always puzzled me. Perhaps we are suppposed to look all sick and pasty, walk with a stoop a shuffle along looking at the ground:lol:
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smcc said:There is no doubt in my mind that the main reasons for the huge increase in type 2 diabetes are the change in diet and the reduction in physical activity over the years.
smcc said:There is no doubt in my mind that the main reasons for the huge increase in type 2 diabetes are the change in diet and the reduction in physical activity over the years.
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