No thans not posible once its damage it stays That way,they are experimenting with transplantatiom but right now not posibleHello
I am a type1 diabetes ;a 17 years old I just wanted to know that could insulin be produced again .actually in my body there is no production of insulin from my pancreas .I am told to use insulin ;I am taking 15 units twice of mixed insulin
No. Type 1 diabetes is a chronic lifelong condition; and as of yet; there is no known cure.Hello
I am a type1 diabetes ;a 17 years old I just wanted to know that could insulin be produced again .actually in my body there is no production of insulin from my pancreas .I am told to use insulin ;I am taking 15 units twice of mixed insulin
Why would you want to decrease your dose? The only thing that matters is whether the dose is correct for you, keeps your BG steady and within range.Ok but then like can the units be decreased as I am taking 30 units of mixed insulin a day
I'm struggling to make sense of this one, but if you're asking 'how much insulin is required for optimal BG control?' then again, that amount is entirely individual depending on so many factors that it's not even worth listing them.And according how much amount of insulin likely required if the sugar levels are normally
Hi. Yes, it's a mis-understanding that T1s have NO insulin production. Many, I gather, may have some but not enough without added insulin but c-peptide shows it.This thread makes my head hurt.
The answer is Yes.
"In summary, results revealed that 1) the ultrasensitive assay, which dramatically improved detection at low C-peptide ranges, found that 10% of patients with disease duration of three to four decades still produced C-peptide"
Source:
http://www.faustmanlab.org/docs/academic/Diabetes Care_March 2012_CPeptide_Faustman et al.pdf
Hi. Do you find you have quite good blood sugar control from the two injections? If you feel you need better control then do consider the Basal/Bolus insulin regime which most T1s have. It does involve 4 to 5 injections a day which is the penalty but better control at each meal is the plus. Discuss with the nurse if necessary.Hello
I am a type1 diabetes ;a 17 years old I just wanted to know that could insulin be produced again .actually in my body there is no production of insulin from my pancreas .I am told to use insulin ;I am taking 15 units twice of mixed insulin
The OP has said that he/she has "no insulin production" - see the initial post. To then ask whether "insulin could be produced again" would imply that the pancreas can REGAIN functionality, which we both know is virtually impossible.This thread makes my head hurt.
The answer is Yes.
"In summary, results revealed that 1) the ultrasensitive assay, which dramatically improved detection at low C-peptide ranges, found that 10% of patients with disease duration of three to four decades still produced C-peptide"
Source:
http://www.faustmanlab.org/docs/academic/Diabetes Care_March 2012_CPeptide_Faustman et al.pdf
@Daibell, the OP has asked whether he/she can produce insulin 'again' and has also stated that he/she has 'no production of insulin'.Hi. Yes, it's a mis-understanding that T1s have NO insulin production. Many, I gather, may have some but not enough without added insulin but c-peptide shows it.
To then ask whether "insulin could be produced again" would imply that the pancreas can REGAIN functionality, which we both know is virtually impossible.
Many thanks for the lengthy and belittling reply @Hoping4Cure; it's much appreciated...Incorrect. You're asserting things which are simply untrue. You have no evidence on which to base this assertion, and there is plenty of evidence that the opposite is true.
Do you know what neogenesis is? Hint: it happens in every human being's body, continuously. Otherwise we could not live. Beta cells included. They continuously grow and replicate, then are killed off for the most part, but if you reduce or halt auto-immunity beta cells will grow back on their own.
My own c-peptide levels have risen in the past two years, so yes, you're absolutely wrong.
Please, don't make confident assertions that regenerating beta cells or reversing type 1 diabetes is "virtually impossible", because that's not what the current research shows. You're going by ideas from the 90s that once beta cells are destroyed there are none coming back to take their place, whereas this would preclude c-peptide levels rising.
I had undetectable levels of c-peptide back in 2011 and now have 0.107 nmol / L (last I checked). That's 0.33 ng/ml if I remember the converted value correctly. Nearly a third of what a non-diabetic's fasting c-peptides are, on average. That's not nothing, and a big improvement over my previous undetectable levels.
Please, don't spread unsubstantiated opinion as fact, or blatant falsehoods.
There are several type 1 diabetics besides myself who have managed to increase their c-peptide levels significantly, at least temporarily. Yes, many of us saw rises and then lowering, but the fact that we've seen rises in lab-verified c-peptide tests, is incontrovertible proof that what you're asserting is false.
https://groups.google.com/forum/#!topic/curetype1/-Q8CeZbDqpk[1-25]
Unless you think several people falsified lab test results from different labs and hospitals in order to trick you?
If you boost c-peptide levels, however that may occur, you've boosted functional beta cells which produce insulin in response to elevated blood sugar. That means mature beta cells can not only survive but replicate and regenerate.
Read this to educate yourself about the lifespan of cells:
https://www.medicalsciencenavigator.com/physiology-of-self-renewal/
"Only a few body parts last most of your lifetime. They are the neurons of the cerebral cortex, the inner lens cells of the eye, and muscle cells of the heart."
Ask yourself this simple question: if functional beta cells are often found in the pancreases of deceased type 1 diabetics who've lived many decades, and nearly all body cell types die off to be recycled and then renewed, what does that imply?
It implies that the beta cells which are found during autopsy weren't created prior to type 1 diagnosis, but rather are recently replicated and/or regenerated. This is just common sense.
@Hoping4Cure, just because I missed out the adjective "full" does not give you the right to speak to me the way you are. Your tone is bordering on aggressive and I will not tolerate that.To date, no one has achieved 100% restored beta cell functionality, at least not without corroborating evidence.
But that's not necessary for clinical significance (even minor increases in c-peptides have drastic effects on health, increased alpha beta cell signalling resulting in reduced hypos, etc), nor what he wrote.
He said it's "virtually impossible" for the "pancreas to regain functionality", which, when one knows how to properly read and parse sentences in the English language, is patently untrue.
"regain functionality" != "regain full functionality"
Without the qualifier "full", his statements are false, period.
I have no sympathy for people making stuff up, passing it off as gospel truth (confident statements made without evidence), then whining about the record being set straight and mis-attributing what they themselves wrote in order to make themselves look better.
Don't make stuff up.
Quoting his responses verbatim:
"To then ask whether "insulin could be produced again" would imply that the pancreas can REGAIN functionality, which we both know is virtually impossible."
INCORRECT.
I have achieved this, two years ago. I have regained partial functionality, which qualifies as "regaining functionality". 100% restoration is not necessary. Permanent restoration either. Because...Logic. If you could even restore even partial insulin production, even for only a brief period of time, that is sufficient to invalidate his claim of impossibility. Do I need to break out a dictionary here? Seriously.
"I just wanted to know that could insulin be produced again"
To which he answered:
"No."
INCORRECT.