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Diabetes Discussion
Type 2 Diabetes
Change of medication
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<blockquote data-quote="Osidge" data-source="post: 318313" data-attributes="member: 17302"><p>Hi</p><p></p><p>Sitagliptin (Januvia) and metformin work in different ways. Metformin works by increasing insulin sensitivity while Sitagliptin works, in part, by ensuring that your pancreas produces insulin when it is required. If a large part of your diabetic problem is insulin sensitivity, then you might find that sitagliptin will not be as successful in lowering your blood sugars. I am on exanitide, that works in a similar way to sitagliptin, and I still take metformin, although now just 1 x 500mg tablet per day, to ensure insulin sensitivity.</p><p></p><p>Hope this helps</p><p></p><p>Doug</p></blockquote><p></p>
[QUOTE="Osidge, post: 318313, member: 17302"] Hi Sitagliptin (Januvia) and metformin work in different ways. Metformin works by increasing insulin sensitivity while Sitagliptin works, in part, by ensuring that your pancreas produces insulin when it is required. If a large part of your diabetic problem is insulin sensitivity, then you might find that sitagliptin will not be as successful in lowering your blood sugars. I am on exanitide, that works in a similar way to sitagliptin, and I still take metformin, although now just 1 x 500mg tablet per day, to ensure insulin sensitivity. Hope this helps Doug [/QUOTE]
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