For keeping your blood glucose levels without too much trouble it can be easier to eat little and often, however, if you can cope without having food, as you do naturally when sleeping or fasting, that too can be beneficial.
I have found that eating either three or four meals per day as in breakfast, lunch, dinner and supper is far too much if you are trying to lose weight, because you could be snacking in between as well.
Portion size is critical, even if you are only having a couple of meals a day.
We just don't need to eat that much as you would believe. The eat well plate diet and even weight watchers means you are eating too much.
It is also a question of getting your balance of protein, fats and carbohydrates in the right balance for you.