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For those worried about cholesterol levels..

As said many, many times on this forum, the total cholesterol is meaningless. It is a total of the good and the bad stuff. If the bad stuff stays the same, and the good stuff increases, then the total will increase. The Trigs/HDL ratio is the important one.
All I know is my doc when I had my yearly blood tests, last one 3 months ago results, my doc said that I was 4.1 total, and all cholesterol was good, so I assume he meant the LDL one also.
 
That's assuming that the Q-risk3 algorithm is accurate. However, it's possible that high blood glucose levels and high insulin levels are worse for you than smoking. Maybe all the stress of having diabetes contributes as well.[/QUOTE Well yes, like most people with medical issues, it stands to reason that if you have a serious medical condition then that would be worse than smoking, but I suppose it is how you look at it. 20 years of smoking can give some people a smoking related disease, yet be dead in the next few, where people with diabetes who do not smoke can go on for much longer. There are many diabetics who have out lived smokers
 
If I remember correctly he does state that smoking is a big cause of CVD and recommends not to smoke, but really everyone knows this so I didn't really think it was important to discuss. He concludes that statins do very little to reduce the risk of CVD and can increase the risk of premature death from other causes. Since he thinks stress (assuming you don't smoke) is the most significant cause of CVD, he recommends trying to avoid chronic stress or at least lower stress levels. Easier said than done, of course. I think he includes both psychological stress (e.g. a stressful job) and physical stress (e.g. elevated air pollution).
Well, you are a bundle of sunshine (Only joking) yes stress can play a big part of it all. Although I have also read that a little stress can do us good. I also read on the BBC interactive health news that even a scare can be beneficial to a heart patient, kind of gives the heart a kick start like an exercise.I must admit though that it gets to the point at times regarding food and medications "What is safe, what is healthy?" Will they tell people in 30 years time fat is bad again? We can only use our own best judgement and sometimes take a step back and look at the bigger picture.Like the LCHF diet is good for diabetes, weight, Etc but it may not be so good for other parts of our body, same with carbs. It really is at times a hard call.
 
Fairly significant but you need to be on about 1 gram per day for it to be of real benefit, at the moment it is not clear as to whether it could replace statins or not. I also seem to remember reading that it can reduce trigs as well but cannot find anything referencing that at the moment.

Do you have a reference for any of this?

What you seem to be saying is that anyone on more than a minimal (500 mg) dose of Metformin has no need of statins. Many here seem to be on 2 or more tablets a day (by my maths 2 * 500 mg = 1 gram) so in theory they should be seeing a drop in cholesterol as if they were on statins.

I find http://www.medscape.com/viewarticle/849463 which seems to have had only 90 T2Ds on Metformin in the study, and seems to be an analysis of existing patients not a trial with controls.

It also says: "Compared with the other participants, those with type 2 diabetes who were receiving metformin had much lower concentrations of the six metabolites — independent of multiple variables (sex, body mass index, physical activity, alcohol intake, smoking, systolic blood pressure, HDL cholesterol, triglycerides, HbA1c, fasting glucose, and use of statins, beta-blockers, ACE inhibitors, and angiotensin-receptor blockers)."

So the 90 T2Ds could also have been on a varied cocktail of other drugs.

The conclusion seems to be that "something is happening but we are not certain what or why".

Most other hits using Google seem to be referring back to this study.

Interesting: http://www.diabetes.org/newsroom/press-releases/2017/petrie-scientific-sessions-2017.html

However, please note (my highlighting):

"REMOVAL studied 428 middle-aged adults with longstanding type 1 diabetes--on average for 33 years. The patients had three or more risk factors for cardiovascular disease, including BMI over 27; A1C greater than 8.0; known CVD/peripheral vascular disease; current smoker; high blood pressure; high cholesterol or triglycerides; strong family history of CVD; or duration of diabetes more than 20 years."

So at first trawl I haven't found anything that seems to say that 1 gram or more per day of Metformin is a potential alternative to statins.

Oh, and statins took my cholesterol way down but the side effects were unacceptable. The 1.5 grams per day of Metformin does not seem to be having any similar effects on my lipid profile.
 
Totally agree. Its never wise to believe it when a doctor says all is good and assume it is. Print outs or on-line results can tell a very different story. :bigtears:
Also that's giving the doc the credit (too much maybe) of knowing what he/she is talking about...
 
Totally agree. Its never wise to believe it when a doctor says all is good and assume it is. Print outs or on-line results can tell a very different story. :bigtears:
Or when they say it is bad (eg total cholesterol). Many, like mine, will just go by NHS guidelines that T2s should have a total cholesterol of 4 or less. She doesn't look at ratios.
 
I've just checked online on my surgeries website and there is nothing on it to join and see my records :(
 
Yes it is your GP receptionist that you need to ask.

Some GPs at bottom of website will display order prescriptions and some gps you can get in to view everything from order prescription... providing you have spoken to reception first and registered... some have a separate website/app to use. Some have both. I think I only know of one surgery that offers nothing...
 
I see you are a person of faith! :)
It is not a question of faith. I have had 4 different doctors and a 2 cardiologist telling me the same. I have been fine for nearly thirteen years so far touch wood hope that it continues. Some people here seem to have more faith in online verdicts or what professors etc are telling us which is all very well, but I think that we have to be sometimes a little skeptic. I see news online about an injection to reverse diabetes and it's a breakthrough that was 3 years ago, where is it? There are so many claims from different medical professions online quite a few with a book on sale, that I sometimes get brain fog lol.I feel sometimes that there is a little NHS and medical bashing on here.It is dangerous as if anybody came on here and was really gullible this could encourage people to stop taking their medication. We all respond differently to medication.
 
It is not a question of faith. I have had 4 different doctors and a 2 cardiologist telling me the same. I have been fine for nearly thirteen years so far touch wood hope that it continues. Some people here seem to have more faith in online verdicts or what professors etc are telling us which is all very well, but I think that we have to be sometimes a little skeptic. I see news online about an injection to reverse diabetes and it's a breakthrough that was 3 years ago, where is it? There are so many claims from different medical professions online quite a few with a book on sale, that I sometimes get brain fog lol.I feel sometimes that there is a little NHS and medical bashing on here.It is dangerous as if anybody came on here and was really gullible this could encourage people to stop taking their medication. We all respond differently to medication.
I would be dead now from prostate cancer after diagnosis 14years ago, if I had not rejected what an oncologist and urologist said and chose a different route to get treatment. D.
 
I would be dead now from prostate cancer after diagnosis 14years ago, if I had not rejected what an oncologist and urologist said and chose a different route to get treatment. D.

I had a near miss along these lines when a Registrar prescribed the chemo regime I would be following. I knew it was the wrong one for my particular type of breast cancer, because I had looked up the protocols. I was going to contact the chief oncologist about it but was beaten to it as he was checking all the prescriptions and saw the mistake for himself. So all was well. Not all doctors know it all. It is always wise to check for yourself. Knowledge is power.
 
I feel sometimes that there is a little NHS and medical bashing on here.It is dangerous as if anybody came on here and was really gullible this could encourage people to stop taking their medication. We all respond differently to medication.

That is because a lot of us have experienced poor to downright dangerous medical advice from healthcare professionals. Once that has happened I'm afraid I for one loose trust in them. Especially when it seems we have been misled on many factors of healthcare by people who learnt stuff 20-30 years ago and have not kept up with progress. I also have a family member who works in marketing for a pharmaceutical company. I for one did stop taking me medication without asking the "permission" of my doctor. One because I had never seen the "doctor", who it transpired knew less about Type 2 than I did, but had only seen the diabetes nurse and secondly because it made me so ill I could hardly function. I took charge of my health with far more effective results.
 
Do you have a reference for any of this?

What you seem to be saying is that anyone on more than a minimal (500 mg) dose of Metformin has no need of statins. Many here seem to be on 2 or more tablets a day (by my maths 2 * 500 mg = 1 gram) so in theory they should be seeing a drop in cholesterol as if they were on statins.

I find http://www.medscape.com/viewarticle/849463 which seems to have had only 90 T2Ds on Metformin in the study, and seems to be an analysis of existing patients not a trial with controls.

It also says: "Compared with the other participants, those with type 2 diabetes who were receiving metformin had much lower concentrations of the six metabolites — independent of multiple variables (sex, body mass index, physical activity, alcohol intake, smoking, systolic blood pressure, HDL cholesterol, triglycerides, HbA1c, fasting glucose, and use of statins, beta-blockers, ACE inhibitors, and angiotensin-receptor blockers)."

So the 90 T2Ds could also have been on a varied cocktail of other drugs.

The conclusion seems to be that "something is happening but we are not certain what or why".

Most other hits using Google seem to be referring back to this study.

Interesting: http://www.diabetes.org/newsroom/press-releases/2017/petrie-scientific-sessions-2017.html

However, please note (my highlighting):

"REMOVAL studied 428 middle-aged adults with longstanding type 1 diabetes--on average for 33 years. The patients had three or more risk factors for cardiovascular disease, including BMI over 27; A1C greater than 8.0; known CVD/peripheral vascular disease; current smoker; high blood pressure; high cholesterol or triglycerides; strong family history of CVD; or duration of diabetes more than 20 years."

So at first trawl I haven't found anything that seems to say that 1 gram or more per day of Metformin is a potential alternative to statins.

Oh, and statins took my cholesterol way down but the side effects were unacceptable. The 1.5 grams per day of Metformin does not seem to be having any similar effects on my lipid profile.
I got it from the Pharmaceutical Journal web site but I cannot access it again as it limits access to articles unless you pay.
http://www.pharmaceutical-journal.c...n-lowering-blood-cholesterol/20069161.article

I think I did say it is unclear as to whether it can replace statins or not at this time.
 
That is because a lot of us have experienced poor to downright dangerous medical advice from healthcare professionals. Once that has happened I'm afraid I for one loose trust in them. Especially when it seems we have been misled on many factors of healthcare by people who learnt stuff 20-30 years ago and have not kept up with progress. I also have a family member who works in marketing for a pharmaceutical company. I for one did stop taking me medication without asking the "permission" of my doctor. One because I had never seen the "doctor", who it transpired knew less about Type 2 than I did, but had only seen the diabetes nurse and secondly because it made me so ill I could hardly function. I took charge of my health with far more effective results.
I am so sorry that you have had such a bad experience, but there are many people who have had very good care. There will always be some people who have been unfortunate, but surely this does not mean that in the grand scheme of things the NHS should be slated entirely. I blame the government to be honest, not enough money going into the NHS for research, bad management and so fourth. I think that most of the medical staff and doctors are doing the best that they can with what they have got to work with.It is also well known that the data on low carb high fat at the moment seem's to be the way to go, but the professionals do admit that this study is early days. Yes, it may be good for people with diabetes etc, but only time will tell if this diet is good for us in the long run and for over all health. There has also been extensive research on vegan diets and people with diabetes have done very well on this diet. People have also done well on low carb such as cous cous, brown rice..very small amounts of these foods. Like I said we are all different, but we cannot be so closed minded as to think that cous cous, brown rice, sweet potato is all bad advice because there are diabetics that are doing well on these foods. The NHS saved my life, resuscitated me, if it were not for them I would not be here.My husband is American and believe me he is not too impressed with American health care. His mother had health issues and all they kept giving her was tablets, tablets for everything.Valium given out like sweeties because she had to pay for her medication and boy is it expensive. We are not doctors or professors.
 
I would be dead now from prostate cancer after diagnosis 14years ago, if I had not rejected what an oncologist and urologist said and chose a different route to get treatment. D.
I was on Amitryptiline for 8 years far to long. My cardiologist was very angry when he knew this ,as he said that it can cause heart arrhythmia, this is before the heart attack, now that doctor that I was with back then, does not mean I am going to blame the whole of the NHS. You will always get good doctors and bad ones, whether they are NHS or not. My sister is with Buba and she had an awful experience with them, so there you go.Good and bad
 
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