HbA1c associated with cancer risk, independent of diabetes

borofergie

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Even more reason to keep your BG under tight control:
The data reveal that chronic hyperglycaemia correlates with increased cancer risk for a number of cancers, except prostate cancer. Evidence is also provided that risk is already increased in the pre-diabetic and normal ranges for several cancers.

These results merit urgent investigation into the risks and advantages of updating recommendations for stricter glycaemic control in diabetic and non-diabetic subjects, as this could help reduce the risk of cancer incidence and mortality.

http://www.nature.com/bjc/journal/vaop/ncurrent/full/bjc2014150a.html

The paper is behind a pay wall, so it's difficult to tell much about the size of the risk, and the influence of HbA1c on it. The fact that they mention "non-diabetic" subjects means that there is probably in increased risk even bellow HbA1c of 7%.
 
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mo1905

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Interesting but you'd be hard pressed to find anything that isn't linked with cancer nowadays !


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paul-1976

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I find the whole 'Starve the cancer cells' by running your body on Ketones instead of glucose theory very positive indeed.
I remember reading a Dr Mercola article a while back on the matter and thinking to myself that maybe my ketogenic diet might save more than just my limbs and eyesight after all.:)
 
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Brunneria

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I remember reading a Dr Mercola article a while back on the matter and thinking to myself that maybe my ketogenic diet might save more than just my limbs and eyesight after all.:)

What is the current thinking about ketones affecting kidney function? I vaguely remember that this was an argument used by the anti-Atkins brigade, but I'm afraid I haven't kept track since then.
 

paul-1976

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What is the current thinking about ketones affecting kidney function? I vaguely remember that this was an argument used by the anti-Atkins brigade, but I'm afraid I haven't kept track since then.

I guess there are a multitude of studies out there on the matter which may conflict with each other and for a while this matter did concern me as I do have reduced kidney function but my anecdotal evidence and that of a few others I've seen on various forums have seen an improvement in eGFR numbers since following LCHF or a ketogenic dietary regime.
 
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borofergie

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Totto

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Not only cancer but also dementia and heart problems are linked to high "normal" bg. So, if the "normal" range makes you ill, is the range really normal?
 
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tonyS54

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What is the current thinking about ketones affecting kidney function? I vaguely remember that this was an argument used by the anti-Atkins brigade, but I'm afraid I haven't kept track since then.

After five years low carb it's had no detrimental effect on my kidney function last GFR >90
 
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Indy51

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Has anyone read Thomas Seyfried's book, "Cancer as a metabolic disease"? I've heard good things about it, but haven't had chance to read it yet.