Search
Search titles only
By:
Search titles only
By:
Home
Forums
New posts
Search forums
What's new
New posts
New profile posts
Latest activity
Members
Current visitors
New profile posts
Search profile posts
Log in
Register
Search
Search titles only
By:
Search titles only
By:
New posts
Search forums
Menu
Install the app
Install
Reply to Thread
Guest, we'd love to know what you think about the forum! Take the
Diabetes Forum Survey 2024 »
Home
Forums
Diabetes Discussion
Diabetes Discussions
Hereditary Spherocytosis and HbA1c
JavaScript is disabled. For a better experience, please enable JavaScript in your browser before proceeding.
You are using an out of date browser. It may not display this or other websites correctly.
You should upgrade or use an
alternative browser
.
Message
<blockquote data-quote="primmers" data-source="post: 175860" data-attributes="member: 31913"><p>I have Hereditary Spherocytosis (HS), which is a form of haemolysing anaemia (the red blood cells are a different shape and the spleen destroys them before they are actually defunct leaving the patient with anaemia) It is often treated by removing the spleen - splenectomy. My spleen was removed over 30 years ago. As is my way, when I have anything odd in my health I do a google check for links with the disorder and HS. I found this 2007 report in the Journal of The American Board of Family Medicine</p><p></p><p><a href="http://www.jabfm.org/cgi/content/full/20/1/93" target="_blank">http://www.jabfm.org/cgi/content/full/20/1/93</a></p><p></p><p>The gist of it is that because the red cells are destroyed prematurely in HS the HbA1c is not a reliable indicator of blood sugar levels over the past three months (which is the normal lifespan of a red blood cell)</p><p></p><p>The report does not specify whether the patient described had had a splenectomy or not. I think it's probable that she had not as I think that the splenectomy generally resolves the matter, BUT it is possible that HS patients who have had a splenectomy might still have shorter lived red cells which would interfere with how the HbA1c should be interpreted. I don't know for sure but I think it's quite important I do <img src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" class="smilie smilie--sprite smilie--sprite1" alt=":)" title="Smile :)" loading="lazy" data-shortname=":)" /> </p><p></p><p>If there are any haeomotologists out there who could answer that one that would be fabby, otherwise I'm going to ask a pal, who works at a high risk maternity clinic where a haematologist attends, if she could check it out with the haematologist for me.</p><p></p><p>As a matter of interest, are there any other HS bods out there? I don't really fit the risk profile for Type 2 diabetes but have it anyway, if there's a lot of us in that boat it might be an interesting research question. HS does have all sorts of knock on effects, funny blood fats, increased risk of heart disease and an increased susceptibility to malaria to name but three so this might be another as yet unsuspected one.</p></blockquote><p></p>
[QUOTE="primmers, post: 175860, member: 31913"] I have Hereditary Spherocytosis (HS), which is a form of haemolysing anaemia (the red blood cells are a different shape and the spleen destroys them before they are actually defunct leaving the patient with anaemia) It is often treated by removing the spleen - splenectomy. My spleen was removed over 30 years ago. As is my way, when I have anything odd in my health I do a google check for links with the disorder and HS. I found this 2007 report in the Journal of The American Board of Family Medicine [url=http://www.jabfm.org/cgi/content/full/20/1/93]http://www.jabfm.org/cgi/content/full/20/1/93[/url] The gist of it is that because the red cells are destroyed prematurely in HS the HbA1c is not a reliable indicator of blood sugar levels over the past three months (which is the normal lifespan of a red blood cell) The report does not specify whether the patient described had had a splenectomy or not. I think it's probable that she had not as I think that the splenectomy generally resolves the matter, BUT it is possible that HS patients who have had a splenectomy might still have shorter lived red cells which would interfere with how the HbA1c should be interpreted. I don't know for sure but I think it's quite important I do :) If there are any haeomotologists out there who could answer that one that would be fabby, otherwise I'm going to ask a pal, who works at a high risk maternity clinic where a haematologist attends, if she could check it out with the haematologist for me. As a matter of interest, are there any other HS bods out there? I don't really fit the risk profile for Type 2 diabetes but have it anyway, if there's a lot of us in that boat it might be an interesting research question. HS does have all sorts of knock on effects, funny blood fats, increased risk of heart disease and an increased susceptibility to malaria to name but three so this might be another as yet unsuspected one. [/QUOTE]
Verification
Post Reply
Home
Forums
Diabetes Discussion
Diabetes Discussions
Hereditary Spherocytosis and HbA1c
Top
Bottom
Find support, ask questions and share your experiences. Ad free.
Join the community »
This site uses cookies. By continuing to use this site, you are agreeing to our use of cookies.
Accept
Learn More.…