I have, in general it seems, steady but raised fasting insulin levels around 6.5mmol/L. Even when not on my prednisolone (forgot it and it has short half-life)
Obviously, I am looking for ways to reduce fasting glucose to non-diabetic levels.
I find it easier to stick to a diet regime that has a scientific basis that I can be persuaded by.
Jason Fung and many others, promote fasting and low-carb but I see no mechanisms proposed (that I understand and hence can evaluate) other than emprical and statistical studies.
This old article proposes a mechanism, indicating amyloids in the pancreas may disrupt a proposed signalling mechanism between the glucagon and insulin secreting cells in T2D.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2342944/
The article relates signalling not in biochemical terms but in control theory terms so is a bit different read than average if you aren't familiar.
It seems to indicate that amyloids are one of the problems and from what i hear is that fasting can help remove these via autophagy, at least in the brain.
Does anyone know of any, more recent or more relevant scientific papers?
Lotties' a nerd today
Obviously, I am looking for ways to reduce fasting glucose to non-diabetic levels.
I find it easier to stick to a diet regime that has a scientific basis that I can be persuaded by.
Jason Fung and many others, promote fasting and low-carb but I see no mechanisms proposed (that I understand and hence can evaluate) other than emprical and statistical studies.
This old article proposes a mechanism, indicating amyloids in the pancreas may disrupt a proposed signalling mechanism between the glucagon and insulin secreting cells in T2D.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2342944/
The article relates signalling not in biochemical terms but in control theory terms so is a bit different read than average if you aren't familiar.
It seems to indicate that amyloids are one of the problems and from what i hear is that fasting can help remove these via autophagy, at least in the brain.
Does anyone know of any, more recent or more relevant scientific papers?
Lotties' a nerd today