Grant, as someone who has, thankfully, never had to endure a transplant, or indeed the journey towards one, I can only comment on my observations.
When I learned these two women were multiple organd transplantees, I had quite a long conversation with them about it. They are (still) members of my local DUK group, even though neither now has their T1. My friends have called their transplants as transformational, but not entirely the eutopian fix.
Both "girls" have an enormous zeal for life, which I adamire enormously, but having been closing in on life's exit myself (many moons ago and all history for me now, thankfully), I understand where that comes from; the firm embrace for something almost lost, but they carry a burden with them.
Transplantation may take away T1, but it leaves behind another maintenance regime that cannot be ignored either, without dire consequences.