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Lantus vs tresiba

Discussion in 'Type 1.5/LADA Diabetes' started by Kristin251, Jan 5, 2019.

  1. Kristin251

    Kristin251 LADA · Expert

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    hello all! Hope you all are well and had a great holiday!

    Insurance had switched me from lantus to Tresiba. Reading about Tresiba it sounds to be more powerful and much longer lasting. It also says it takes 4-6 days for the full effect. Some people say thier sugars are not steady. I was taking 4 units of lantus and will continue that dose with Tresiba until I find differently. Lantus never lasted until morning. I’d get a sharp spike after 3 am and need a bolus correction.

    So my question is ,
    How do you think Tresiba compares to lantus or levimere?
    Is it harder to control?
    Do you need less bolus for food?
    Any side effects? I hear edema and weight gain are very common.
    Any nuances I should know about?

    I was used to lantus being gone well before I woke up and just relied on humalog during the day.

    I’m not sure if my diet matters but I eat beef, salt, seltzer and wine only. Nothing else. This has improved my health greatly but it’s a bit harder to control bs.

    Thanks so much for any and all advice and comments.
     
  2. Knikki

    Knikki Type 1 · Well-Known Member

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    Hello @Kristin251 I moved from Lantus to Tresiba a few months ago, mainly because like a lot of people I was finding that Lantus was more 15-18 hours instead of 24.

    Tresiba has a much flatter profile, which suits me as a back ground insulin and I have found that any dose changes I make do take something like 3-5 days to take effect, because it has a 72 hour window of effect.

    I found that once I settled on a dose then control was ok, but I did find that taking it of a night time pushed my levels way low, so changed to first thing in the morning. But that's just me, you are on a lower dose so will have to find what works for you.

    Good luck.
     
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  3. Kristin251

    Kristin251 LADA · Expert

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    Thank you SO much for replying. I read reviews online but we know how those go...
    I took it last night as my second dose and see changes today already. I was taking 4 lantus but was waking up much higher than I like. 5 units and I’d hypo.
    So I started Tresiba with 4 but I think to be safe I’ll vack down to 3 and see.
    With only 4 units at 10 pm of lantus I think it’s was well gone before I woke up and I got no daytime help. I had to inject a half unit humalog every two hours to stop the rise. I’m hoping Tresiba will help during the day. My fasting was much better this morning and I actually dropped a little after breakfast. That never happened with lantus. So I’ll play it safe and monitor even more often until I find out how I respond.
    If you take it during the day do you go low at all?
    Did you find you need less basal?
     
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  4. Kristin251

    Kristin251 LADA · Expert

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    Thank you so much again
     
  5. Knikki

    Knikki Type 1 · Well-Known Member

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    I usually run low anyway, it is just the way I like to work this wonderful condition, but I find it easier to manage during the day because I have a Libre so I can catch any potential hypo or hypers that may develop.

    Less basal? No not for me, but others on here who use Tresiba have reduced the amount they used. After a few weeks of trying different doses I eventually pushed mine up by, I think, 1 unit.

    But like I said earlier I use way more than you do being full blown T1 :)

    Like most things it is trial and error, if you make any changes to your Tresiba dose just be aware that it might take a couple of days before you see any effect :)
     
  6. Kristin251

    Kristin251 LADA · Expert

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    I am full blown type 1 as well. No insulin left.
    I appreciate you taking the time. Changing insulin is scary. They originally switched me to basaGlar and it was like water. Did nothing at all.

    I too like to run lower bs. My bingo number is 85. Last 2 A1C s were 4.7 and 4.8. But I’m blousing left right and sideways. Hoping Tresiba will help through the day.

    Do you think, since I eat zero carbs other then wine that it might make a difference in dose? I just eat fatty beef.
    I think I’ll drop to 3 units tonight. I’d rather not fight hypos for days.
    So when you switched to day bolus it was better because you had a libre and you can catch it ? I’ve been testing in the middle of the night for awhile as lantus required a bolus then. So no biggy.
    Last question...do you see a peak? Or is it pretty consistent?

    Thanks again. It’s makomg me feel more comfortable.
     
  7. Knikki

    Knikki Type 1 · Well-Known Member

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    Oh sorry @Kristin251 did not realise you were a Type 1 your status says LADA - Expert :)

    TBH I'm not sure if wine has any carbs :) but I'm afraid I can't help you on that because for me anything in on the menu, carbs, fats, proteins etc and have weakness for chocolate, sweet tooth diabetic is me :hilarious:

    So far Tresiba holds level for me, the only peaks I see is when I have eaten something that has a slow digest, carb release like curry.

    When I first changed from Lantus to Tresba I was advised "you should drop your dose by 2 units" which I did but I found that made me run uncomfortably high, for me anyway, so slowly I pushed the dose back up, which at last check my Hb1ac was 5.7% so not to bad :)

    I can't advise on the amount of insulin your dropping, just take care and look after yourself.
     
  8. Kristin251

    Kristin251 LADA · Expert

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    Thank you again. I think the fatty beef I eat changes the game but I feel so much better without any carbs or fiber. Allergies cleared up 95%, all aches, pains and bloating gone. Numerous other benefits so I’m staying with it. I’ll figure it out. I always do. I guess I’d just not like to stick myself so often during the day. Fasting wasn’t so good today but it’s only been 3 doses and I did reduce it. I wonder how splitting my doses would work? I might try that. Like 3 before bed and 1 in the morning.
    One last.... do you know the time it takes affect? I’ve seen everything between 4-8 hours. This might help me decide to split or not. Then I think I’m done with my questions lol. You’ve been a big help. I appreciate it!
     
  9. Knikki

    Knikki Type 1 · Well-Known Member

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    @Kristin251 Tresiba is classed as an "ultra long" insulin which should an effect of up to 42 hours an is designed as a "once a day" insulin.

    It is one of reasons I wanted to change from Lantus because I was split dosing because I just wanted a background insulin to keep a lid on things. It does work most of the time and I like the way it works with Apidra the fast acting I now use.

    Sometimes things do wrong and have woken up on a 24.5 but fortunately that has only happened once, most of the time it keeps me lower than 10 (that's mmol/ml UK measure) which works for me.

    I am really not sure how "split dosing" would work as the insulin is just not designed to be like that.

    Others that I know who use Tresiba only inject once a day, but your the only T1D I know of who is on small doses, I mean I inject 23 units a day of it.

    Sorry I can't be more helpful than that, it's just outside my knowledge base. :)

    What ever you do or decide to do take care and take things easy as, already said, Tresiba can take a couple of days to work into your system.
     
  10. Kristin251

    Kristin251 LADA · Expert

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    Awesome. Again. Thank you. I’ll just play around for now. Not much else I can do :) you’ve given me comfort. Thanks for sharing your experience!
     
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  11. LRD

    LRD LADA · Member

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    Thanks for the information here. Someone wanted to try me on Tresiba, but I thought it was for type 2 only and refused to do so. I also wanted my endo to confirm it. I am a LADA and also insulin dependent. I think I will ask my endo for it as I hear it is only once a week. Thanks again.
     
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