phoenix
Expert
- Messages
- 5,671
- Type of diabetes
- Type 1
- Treatment type
- Pump
Ian's point was that his diet hadn't caused him to have a hypo but the DUK advice is aimed at all with T2 at whatever stage or set of medications they are taking and has to give warnings.
Stephen is correct to say that hypos are drug induced however many T2s are taking oral hypoglycaemic drugs. The very next statement on the webpage mentions adjusting medications. In the full statement rather than the web update/summary these two statements are I think more linked together.
People on sulfs and mixed insulins would be very much at risk of hypos if they reduced their carb intake without careful adjustment of their medications.
The organisation uses evidence to write their statements so I wondered what evidence is there? I did a quick search using low carb/hypoglycaemia. The very first hit I got was the Yancy, low carb study which states that as part of it's protocol they adjusted medication as a result of hypoglycaemia. They also mention one subject (it wasn't a large trial) who had needed help from paramedics after missing a meal.
We had a discussion about the risks of hypos for T1s recently, in some ways we tend to expect them and the risks are certainly there. The risks are also there for T2 . Some sulfs in particular are thought to shut down protective mechanisms leading to prolonged hypos.* If the person is older, they may be even more susceptible to further risks (falls, heart attacks and strokes caused by the hypo)
This study looked at the 102 cases of comas due to hypo (drug caused) in a hospital in Israel over 7 years; 92 of them had type 2, only 10 type 1..(median age 72)
http://archinte.jamanetwork.com/article.aspx?articleid=414829
* https://www.inkling.com/read/pharma...-egan-1st/chapter-31/oral-hypoglycemic-agents
Stephen is correct to say that hypos are drug induced however many T2s are taking oral hypoglycaemic drugs. The very next statement on the webpage mentions adjusting medications. In the full statement rather than the web update/summary these two statements are I think more linked together.
People on sulfs and mixed insulins would be very much at risk of hypos if they reduced their carb intake without careful adjustment of their medications.
The organisation uses evidence to write their statements so I wondered what evidence is there? I did a quick search using low carb/hypoglycaemia. The very first hit I got was the Yancy, low carb study which states that as part of it's protocol they adjusted medication as a result of hypoglycaemia. They also mention one subject (it wasn't a large trial) who had needed help from paramedics after missing a meal.
We had a discussion about the risks of hypos for T1s recently, in some ways we tend to expect them and the risks are certainly there. The risks are also there for T2 . Some sulfs in particular are thought to shut down protective mechanisms leading to prolonged hypos.* If the person is older, they may be even more susceptible to further risks (falls, heart attacks and strokes caused by the hypo)
This study looked at the 102 cases of comas due to hypo (drug caused) in a hospital in Israel over 7 years; 92 of them had type 2, only 10 type 1..(median age 72)
http://archinte.jamanetwork.com/article.aspx?articleid=414829
* https://www.inkling.com/read/pharma...-egan-1st/chapter-31/oral-hypoglycemic-agents