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Newcastle diet journey

Here are some of the results from the original study on Newcastle diet:

The study demonstrates that the twin defects of beta cell failure and insulin resistance that underlie type 2 diabetes can be reversed by acute negative energy balance alone. A hierarchy of response was observed, with a very early change in hepatic insulin sensitivity and a slower change in beta cell function. In the first 7 days of the reduced energy intake, fasting blood glucose and hepatic insulin sensitivity fell to normal, and intrahepatic lipid decreased by 30%. Over the 8 weeks of dietary energy restriction, beta cell function increased towards normal and pancreatic fat decreased. Following the intervention, participants gained 3.1±1.0 kg body weight over 12 weeks, but their HbA1c remained steady while the fat content of both pancreas and liver did not increase. The presented data provided clear evidence that decreasing total pancreatic fat is associated with a return of beta cell function.
The presented study demonstrated for the first time the early time course with which both hepatic fat stores and hepatic glucose production fall in response to dietary restriction in type 2 diabetes. Change in peripheral insulin sensitivity played no part in the early return of normoglycaemia.

As we can see, results are very promising, so keep going and good luck!!!


Lim EL, Hollingsworth KG, Aribisala BS, Chen MJ, Mathers JC, Taylor R. (2011) Reversal of type 2 diabetes: normalisation of beta cell function in association with decreased pancreas and liver triacylglycerol. Diabetologia: 54(10): 2506-14.
http://www.ncbi.nlm.nih.gov/pubmed/21656330
 
The hypocalorific nature of the diet is not important. The experiment followed the observation that those who underwent bariatric surgery appeared to be cured of their diabetes. That is the reason why they went for the very low calorie and speedy weight loss approach. Prof Roy taylor explains this in the FAQ

The particular diet used in the study was designed to mimic the sudden reduction of calorie intake that occurs after gastric bypass surgery. By using such a vigorous approach, we were testing whether we could reverse diabetes in a similar short time period to that observed after surgery.

The essential point is that substantial weight loss must be achieved. The time course of weight loss is much less important.

It is a simple fact that the fat stored in the wrong parts of the body (inside the liver and pancreas) is used up first when the body has to rely upon its own stores of fat to burn. Any pattern of eating which brings about substantial weight loss over a period of time will be effective. Different approaches suit different individuals best.

In fact, Roy Taylor doesn't recommend a fast and furious diet:

Previous research has shown that steady weight loss over a 5 – 6 month period is more likely to be successful in keeping weight down in the long term. For this reason, I would not recommend a very low calorie diet initially for most people with type 2 diabetes.


http://www.ncl.ac.uk/magres/research/di ... dy_000.pdf
 
Hello everyone.
I have just joined today, hoping to share my experience of ND and benefit from all your experiences too.
I was diagnosed with type 2 about 24 yrs ago. My Hba1c was 9.8 and fasting blood sugar 17 although for more than 10 years different doctors had told me without carrying out any tests that I was not diabetic. I was apparently too old for type 1 and too young for type 2! I had thrush in all my 'warm' places even behind my ears and the corners of my eyes, numb areas on my feet and non-fatty liver disease.
4 months of dietary control sorted that out and gave me an Hb1ac of 5.7
From there it has been downhill via medications that worked for a while and then metformin which worked well but made me really ill, and then insulin which really gave me my life back.
So I was really excited at the prospect of 'reversing' my diabetes when I read about the Newcastle Diet.
I spoke to my (locum) GP who prescribed the Optifast and suggested I return in 4 weeks at which time I saw another (dare I say very fat) different locum who declared the diet 'not compatable with human life' .
I felt this was quite liberating as it left me free to follow my own choices.
Unfortunately it also completely demotivated me! of which I am really ashamed and I started eating 'food' again, and having got off insulin again have to use it.
I am trying to get started again, but I live in the north of Scotland and it is now quite cold and just using the shakes and the diet soup and making the veggies into soup is making it extremely difficult to keep warm. I am wearing 3 fleeces just now and feel the only way to get warm is to soak in a hot bath and go to bed early with 2 hot water bottles and 2 duvets!
I would like to know if others are having the same sort of experiences and what coping strategies they have discovered.
Or maybe, someone will be brave enough to tell me to stop whingeing, stop being a wimp and just get stuck in there!
My current Hbaic is 7.8. My next diabetes clinic is 21st Jan and my plan was to go back with and Hba1c of 5 point something. It obviously isn't going to happen now, but even a 6 point something would be brilliant.
All helpful advice greatly appreciated.
 
Hi Sugarbabe.

I managed about 5 weeks and lost about 1 1/1 stone and my glucose readings were getting better. Unfortunately a combination of personal problems left me turning to 'food' although not to the extent I would have done previously. I am away this weekend but have ordered enough shakes to last me to Christmas starting again on Tuesday.

I guess in Scotland you will be cold without the diet, its cold enough here in Cheshire! How far in are you? I think the feeling cold is supposed to subside.

As for only having soup, I found oven roasted veggies using fry lite and a little balsamic, or cauliflower rice to be good for food to 'chew'. French onion soup leaving onions very chunky helped too.

I was never too strict over the total calories of my veg servings, although a few weeks in I discovered the my fitness pal app where you can work it all out!

Which shakes are you using if your gp won't back you up? I'm using ready made slimfast shakes as they fit in easy with a busy lifestyle, plus the cafe latte one makes a lush breakfast with ice! They are half price on superdrug at the moment, plus with a voucher code I just ordered 30 days worth for £60, not bad.

Good luck, and don't let your gp demotivate you, I never consulted mine for that very reason!




Sent from the Diabetes Forum App
 
Hi


I would suggest Slim and save as they have a good range of soups. They also have low car meals just add boiling water.

I have only tried one or two of the meals, I wasn't that impressed but they would make a good sauce for cooked veg.

The shakes and soups I would recommend. As well as their own website they do have offers on Ebay

Go for it! At least until Xmas, then take a break and see how you go.

It has done wonders for me

Cara
 
Well I am fortunate not to have had any side effects such as headaches tiredness etc., but as I am coming to the end of day 3, I feel really fed up and depressed!! It was a real struggle to eat the soup I'd made for supper, and the shake tasted awful ( the same shake that I found more than palatable yesterday!). All this despite being quite hungry. I suppose the fact that I normally have a very varied diet, and am finding this boring might have something to do with it, but I have a dreadful feeling that I am going to have trouble sticking to the regime. Does anyone have any interesting recipes please? I checked the Newcastle MRI centre website, but the recipe page would not load. All the vegetable recipes I have contain cheese, oil, butter or all sorts of other forbidden goodies.

All ideas gratefully considered!

Hi i know this is a few months old now but thought i would reply anyway. I love Cauliflower Mash, i know some do not, but i just love it, i like all veggies, favorite is Brussels sprouts, but because i am also on warfarin, i have to eat them sparingly because they have something that thins the blood and mess with my warfarin which does that job.
So give the Mash a go, little salt, little pepper, Very little cheese on top, squeeze the water out before mashing as it will tirn to mush instead of mash lol.
 
Hi i know this is a few months old now but thought i would reply anyway. I love Cauliflower Mash, i know some do not, but i just love it, i like all veggies, favorite is Brussels sprouts, but because i am also on warfarin, i have to eat them sparingly because they have something that thins the blood and mess with my warfarin which does that job.
So give the Mash a go, little salt, little pepper, Very little cheese on top, squeeze the water out before mashing as it will tirn to mush instead of mash lol.
Hi Jimmy, thank you for replying, and all the tips. I did eventually get my head around things and get myself sorted out. Sprouts are my favourite too. Sorry you have to be deprived of them.
I've used cauliflower mash before, but had forgotten about it. What I hadn't heard of was the cauliflower rice!!! I've been using it for a while now--- as well as the mash ( I find if you use a hand held liquidiser, instead of a traditional potato masher and make sure its well drained, the texture is great---- it fries too after mashing-- makes little fried cauliflower mash balls, or flat cakes--- great with breakfast-----) If you're on the ND you can just put the "rice grains" in the microwave---- no water and use like boiled rice. I saw recipe for cauliflower pizza base on this forum too, which I intend to try, and also believe it or not (not here ) cauliflower bread! What a versatile veggie it is!!!

I did three two week session on the ND, and am going to do another couple now that Christmas and new year are over. It might sound horrendous to do, but once you get yourself sorted out, and a few good recipes, it's actually (for me) easier than trying to stick to a 1000 Kcals a day diet..
 
Thanks for that reply very reassuring for this old fella lol, i am going to have the Mash again this evening , can i ask what you have with it or do you have it on its own, been reading a little about canned sweetcorn, may just rinse and make some kind of patties, mix it in with the Mash and fry.
After a day on the ND yesterday i felt fine, woke up this morning my fasting level was 11.2 (usually in the 20's) so was very pleased, had my Tesco chocolate Ultraslim two hours later it was up to 20.2, was disappointed in that.

Jim
 
Thanks for that reply very reassuring for this old fella lol, i am going to have the Mash again this evening , can i ask what you have with it or do you have it on its own, been reading a little about canned sweetcorn, may just rinse and make some kind of patties, mix it in with the Mash and fry.
After a day on the ND yesterday i felt fine, woke up this morning my fasting level was 11.2 (usually in the 20's) so was very pleased, had my Tesco chocolate Ultraslim two hours later it was up to 20.2, was disappointed in that.

Jim
.
When I fry it, I use it on its own, but reading your reply, I used to make patties with potatoes, cheese and bacon, so I might just try them with the cauliflower mash. Not while I'm on the diet though!! I found I had to come off my meds when I did the diet, cos I went too low, but had to start again afterwards --- although only half the original dose. I would think any non starchy veg would mix in with it. How are you with cabbage? (another one of my faves Or broccoli?

Check the contents of your shake, I live in Spain, and all the diet shakes made locally are sweetened with sugar!!! I ended up buying French made shakes from UK. They taste very sweet to me, but are very low in carbs, using aspartame, and other artificial sweeteners
 
Ah Ha, my Brother and sister both live in Spain (Costa Blanca), Yes Broccoli, do love that, and Cabbage not a fav but yes i do like it. Sorry you have problem getting your shakes in Spain, have you tried ordering through "Amazon", or Ebay. What shakes are you using, i am using Tesco Ultraslim, which may be wrong just waiting to hear back from somebody else on this Forum.

Jim
 
Hi. This is my first post. I hope some people out there can help answer some questions for me.
I was diagnosed with Type 2 about 2 1/2 years ago. I have been using Metformin, plus diet, and exercise to regulate blood glucose. This has been successful. I started the ND on Monday, so this is day 3, and I think I'm hitting "the wall". I'm getting some funny readings on blood glucose. At bed time they are down to the low 5's, but in morning have risen to high 7's. This is in spite of not eating or drinking after 8pm. Why is this happening? Normal day time readings are down to low 5's again 2 hrs after shake breakfast.
I am continuing to take my Metformin, plus statin and BP tablet. Should I not take the Metformin while on the ND?
When I began the diet my weight was 98Kg. I hope to stay dieting until this reduces by 20%. Then start a maintenance low card diet. Any suggestions?
 
Hi Pembers

Our levels are higher in the morning probably because of the dawn phenomena or Liver Dump, have a search on the form there are quite a few posts on it.

It has been said that the morning fasting levels are the last to fall.

You will have to check with your GP about your meds. You may need less as you have less going in!

Good luck and let us know how you get on

Cara
 
Good morning Cara, those Tesco shakes must be doing something right , as i have written before, three days ago i was waking with levels at around 27, even been at 32.2, my levels are down to 9.9 this morning, i am going to stick with them shakes for now and see how i progress rather than move to far into the realms of Doubt and confusion lol.
Why are medical journals not jumping for joy with these findings as they should be, ah there is the doubt and confusion again lol.

Jim
 
Great results so far.
It is worth sticking with it as results are good. Although it gets harder once the novelty wears off.

Keep an eye on your results and report back!

I am wearing clothes that haven't fitted me in years!

Cara
 
Cara i am pleased it is all working for you, do you have a favorit evening meal, i have to keep away from to much Vitamin K as it messes with warfarin, makes life a little more difficult.

Jim
 
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