Not one but three questions..

[Cherryred]

Last night I was reflecting on the last three evenings after dinner readings of 8.3, 10.2 (most likely higher at 3 hours post meal but I didn't check) and last night at 3 hours, 12.8. I manage to keep my BS very even all day in the 5-6's, as I really am conscious of the carbs I ingest, plus I walk after meals. We had guests for dinner Sunday evening and I did indulge in a glass or 2 of wine, roast potatoes and a slice of cheese cake. Last night I ate the leftovers and I went from 5.8 to 12.8 over a span of 4 hours. My question is this, what happens with that high blood sugar? My understanding is my body didn't produce enough insulin to help the glucose get into my cells prior to diagnosis. Is the same thing happening when I eat dinner that consists of too many carbs for the insulin that I do currently have from the basal and I that I still am making on my own?

Second question is regarding metformin, my doctor put me on 1000 mg at diagnosis and when that didn't help he quickly increased the dosage to 2000 mg. When that didn't work and my numbers were still high despite me starving myself, they added lantus which worked and brought my numbers down. I am not used to taking medication and it makes me uncomfortable to needlessly take an extra 1000 mg when it may not be necessary. I feel doctors are excellent at piling on the pills and I wonder if taking 1000 vs 2000 really makes any difference. Perhaps this issue is just me adjusting psychologically to this new normal and I should just take the 2000 mg without question. I did ask my endo if I needed 2000 and he shrugged his shoulders and said it was fine.

Lastly have any of you ever had your genetics done? I had signed up for 23andme last year to find out ancestry and they added the health overview a few months back. I took a close look to see if there were any diabetes genes in my raw data and it was very interesting to learn that I do have the 2 genes that predicts 18x greater risk of type 1, as well as numerous other predictors such as gestational(which I had) and type 2. If any of you have done this or have any expert advise on this I would love to hear from you.

Whew..if you made it this far reading thank you!

 

[novorapidboi26]

Any excess glucose in the blood that can not be absorbed into the cells of your body will spill over out into your urine..........there will be a threshold for each individual where this happens, but I think the majority of the time it will get absorbed......whether that be when your own insulin becomes more effective due to decreased resistance/more production or when more insulin is introduced manually.......

I suppose the only way to find out if you need the metformin is to reduce it, but you would need to get permission from your doctor......it may well be that injecting insulin may be enough to keep things under control, but these things should be adjusted over time.....

I haven't had any genetic tests done like that.........I have recently took part in a genetics study that my clinic was participating in..........may be a few years before any data is produced though.......

 

[phoenix]

Cherryred,
If you've been looking at the raw data and perhaps seen an odds ratio of 1.18 for a T1 SNP I can try and explain a bit if that's what you want .
What were the SNPs that you were looking at?

 

[Cherryred]

Hi Phonenix..
Yes, that is what I want, a dumbed down understanding of the data.
This is what I found, what I was trying to determine if I can figure the type of d based on my SNP results, specifically LADA.
rs9272346(A;A) rs7903146 (C;T) rs7574865 (G;T)
rs1801282 (C;G)<which tells me to watch out for high fat, it actually said that.

 

[Daibell]

Hi. Most diabetics produce some insulin; even long-term T1s. Ref the Metformin adding to a dose is not a linear law i.e. 2000mg doesn't work twice as well as 1000gm. I've been on 2000mg for 10 years and I did suggest to the DN that I no longer needed it. She said it had protective properties so worth having. I have also read it improves insulin performance slightly. As Met is a very safe drug with few downsides I wouldn't worry too much about taking it.