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Novarapid vs Humalog

Discussion in 'Type 1 Diabetes' started by Richard F, Jul 10, 2020.

  1. Richard F

    Richard F Type 1 · Well-Known Member

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    Hi all

    Talking to the clinic today we discussed ways of getting a more rapid result from an injection. I take multiple correction doses, carb count etc. Last HbA1c 53%. They suggested swapping from novarapid to humalog.

    Anyone done this? Did they find it was faster acting?

    I'm campaigning for a pump at the moment.
     
  2. kev-w

    kev-w Type 1 · Well-Known Member

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    I can't help you with your question but :p have you read up on 'FIASP' (fast insulin apspart) which (I believe) is a faster version of Novorapid, it's available on the NHS and some folk have had decent results with it on mdi (it was brought in for pumps) but then again some folk didn't get on with its shorter lifespan.

    You do rotate injection sites and use fresh needles of course :)
     
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  3. In Response

    In Response · Well-Known Member

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    I was on NovoRapid for years. Like many, when I started using the LIbre, I realised how long it was taking to start working. I switched to Fiasp which was better but had some "stability problems" (it would suddenly stop working.
    I was then offered Humalog to trial. Wow, I found it s-l--o-o-o-o-o-o-o-w. For me, it was slower than NovoSluggish but we are all different so I would not discount Humalog based on just my experience.

    In the end, I worked out the Fiasp stability problem was due to having a shorter shelf life (I don't use much). With that in mind, I have been back on Fiasp for more than 6 months and found it the faster of the three (NovoRapid, Humolog and Fiasp).

    But I can't over emphasise how different we all are. Trialling Humalog shouldn't stop you going back to NovoRapid (or trying Fiasp) if it doesn't work out for you.

    P.S. I have a pump. I think having a faster acting insulin is even more important in a pump because one of the strengths of teh pump is being able to change basal rates quickly. There is no point being able to suspend basal for exercise when I have to do it 90 minutes before I start when 90 minutes gives my family and colleagues the chance to cancel the exercise.
     
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  4. Richard F

    Richard F Type 1 · Well-Known Member

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    Thanks both

    Doc tells me Fiasp is very marmite.

    I think I need to discuss with the diabetic team some more.
     
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  5. MarkMunday

    MarkMunday Type 1 · Well-Known Member

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    I have used both and I could see no difference. For me the time to peak and duration of insulin action were pretty much the same. If you want something faster, ask for Fiasp or Lyumjev (new from Eli Lilly). They are not suitable for low carb eating with MDI, though. But should work well with a pump.
     
  6. Richard F

    Richard F Type 1 · Well-Known Member

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    Thanks, maybe the doc is trying to distract me from my pump request.

    What do you regard as low carb? I'm on around 120 per day.
     
  7. MarkMunday

    MarkMunday Type 1 · Well-Known Member

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    I would call that 'moderate carb'. If it works for you, great, but going lower would further stabilise blood glucose.. 'Low carb' is defined in different ways but is often understood as the level of carb that retrains the body to switch from glucose to fat as the main source of energy. Doing that requires getting into and staying in dietary ketosis. That in turn involves consuming less than 50 grams of carb a day. In my case it has really stabilised blood glucose.
     
  8. Richard F

    Richard F Type 1 · Well-Known Member

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    Thx
     
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  9. Richard F

    Richard F Type 1 · Well-Known Member

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    The doc has added humalog to my script, I'll see how I get along.
     
  10. Richard F

    Richard F Type 1 · Well-Known Member

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    I've been using humalog for 5 days now, not quite as straight forward as I'd hoped. I seem to be struggling balancing things particularly over night.

    I'm thinking I might need to adjust (increase) my basal, although I can't logically see why. Typically it takes me about a week to get used to a new basal dose, the last time it took me a month to get it right (reduced in stages from 18 to 12)

    Is it usual to rebalanced basal (lantus) when the bolus type has changed?
     
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  11. Rokaab

    Rokaab Type 1 · Well-Known Member

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    I wouldn't have thought so as your basal should be independent of your bolus - though it is possible that the Novorapid was staying around in your system for much longer than you expected - thus effectively adding to your basal for some amount of time?
    I know when I was on Novorapid it could be very slow and sat around for ages (as in I often saw it kicking in about 4-5 hours after I'd taken it, thanks to my libre)
     
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  12. porl69

    porl69 Type 1 · Well-Known Member

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    I wouldn't think so BUT it is a good idea to do a basal test every now and again especially when your BGs start mis-behaving!
     
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  13. Richard F

    Richard F Type 1 · Well-Known Member

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    I think you may be onto something. Since starting with humalog I've reviewed my libre graphs, I'm often seeing a second peak 2-3 hrs after eating which I then have to correct.
     
  14. Richard F

    Richard F Type 1 · Well-Known Member

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    Well for anyone finding this thread.
    2 weeks in and getting used to humalog, a few hypos but now I recon I've a handle on it.

    For me it comes in quicker and leaves quicker than Novarapid, it seems to peak about the same time 2 hrs in then drops off, Novarapid seemed to be active for longer.

    Time in target up to over 70%, from around 65%, and much less time spent really high.

    Overall more controllable.
     
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