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Research and Metformin

Discussion in 'Metformin/Biguanides' started by Osidge, Feb 4, 2018.

  1. Osidge

    Osidge Type 2 · Well-Known Member
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  2. Pipp

    Pipp Type 2 · Expert
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    I think we each need to do our homework, then apply findings to our own individual circumstances
     
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  3. Osidge

    Osidge Type 2 · Well-Known Member
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    Of course we do and this is a contribution from research that might help some people to think about this particular medication.
     
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  4. Pipp

    Pipp Type 2 · Expert
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    Indeed, and it can be so difficult with all of the conflicting information. I find it important to reassess my own needs from time to time, as I have several medical conditions, and the need for much medication. I do prefer to take as little medication as possible, concerned about polypharmacy as I get older. Though I do believe Metformin to have benefits for some and when I did take it was fortunate not to have the uncomfortable gastric problems some people report. The meds don't always compliment each other, and there can be reactions and side effects. I often find the friendly local phamacist to be more knowledgeable about the meds than the G P.
     
  5. Mike D

    Mike D Type 2 · Expert

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    Downsides to everything .. just like statins.
     
  6. Pipp

    Pipp Type 2 · Expert
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    Sure are @Mike D , advantages and disadvantages need to be considered by the individual, taking into account their own circumstances.
    I think I already said that, though.


    Edit to correct member alert
     
    #6 Pipp, Feb 4, 2018 at 2:20 AM
    Last edited: Feb 4, 2018
  7. Osidge

    Osidge Type 2 · Well-Known Member
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    Hi @Mike D There are certainly possible downsides to a lot of things and medications are not immune from that. There is, however, a world of difference between possible downsides and actual downsides. Sadly some people have a down on certain medications because of possible adverse effects which they may never experience thereby missing out on known benefits and on emerging benefits from past and continuing research.
     
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  8. Mr_Pot

    Mr_Pot Type 2 · Well-Known Member

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    There are probably better resources for research than the marketing manager of a software company.
     
  9. Osidge

    Osidge Type 2 · Well-Known Member
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    My post was directional. Of course there are many reports on past and current research into metformin. Let Mr Google be your friend. Interestingly, when my GP wanted to stop my metformin as my numbers were normal, my endocrinologist advised against that and advised me to go onto the highest daily dose of metformin, if I could tolerate it, because of the emerging benefits. I can and I did.
     
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  10. davidopong

    davidopong Type 2 · Well-Known Member

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    Very interesting read. Is Metformin such a magical drug or the article's extolling of the drug is actually for marketing purposes?
     
  11. NoCrbs4Me

    NoCrbs4Me I reversed my Type 2 · Well-Known Member

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    I had to turn my adblocker off to see it.
     
  12. Osidge

    Osidge Type 2 · Well-Known Member
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    Why would you think it is for marketing purposes? There is nothing magical about repurposed drugs. Many are now being researched for medical problems other than the one they have originally been approved for.

    https://www.google.co.uk/amp/s/www.endocrineweb.com/amp/18692
    http://www.metabolismjournal.com/article/S0026-0495(03)00408-6/pdf
     
    #12 Osidge, Feb 19, 2018 at 10:51 PM
    Last edited: Feb 19, 2018
  13. Osidge

    Osidge Type 2 · Well-Known Member
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    i did not have that problem with my ad blocker.
     
  14. Resurgam

    Resurgam Type 2 (in remission!) · Expert

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    Does needing to wear a nappy count as looking younger?
     
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  15. Osidge

    Osidge Type 2 · Well-Known Member
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    If that is what it means to you. It certainly does not figure in my thinking.
     
  16. Deepshika

    Deepshika Type 1 · Member

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    Have you experienced any kind of side effects?
     
  17. Osidge

    Osidge Type 2 · Well-Known Member
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    None whatsoever.
     
  18. zand

    zand Type 2 · Expert

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    I wish I could still take metformin. My surgery won't allow me to have it because my BG's are in the pre-diabetic range now.
     
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  19. Osidge

    Osidge Type 2 · Well-Known Member
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    My surgery tried that on me but I resisted it and got my Endocrinologyst to back me. That worked and my Metformin was raised from 3 to 4 tablets a day instead of going from 3 to none!
     
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  20. zand

    zand Type 2 · Expert

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    I don't have an endocrinologist unfortunately, I am only seen by my GP in respect of my type 2.
     
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