Hello, my GP changed my gliclazide(2tabs twice a day-can't remember the dosage) to 1x100mg per day. I''ve been on this for about 2 months. My blood/glucose has gone from an average 8 to to mid to high teens, along with the associated problems with high BS - fatigue, thrush etc. Trying to get an appointment with GP is impossible so I'm hanging on til I go to the hospital diabetic clinic in a couple of weeks. Has anyone else had this problem with Sitagliptin or perhaps I'M on the wrong dosage? Any thoughts??