https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399621/... if a person has true type 2 diabetes, then they have more fat than their beta cells can tolerate.Hello,
Thanks for reading!
I've been on a keto diet for 4 weeks and low calorie (I don't count calories but I have a rough idea of how many calories I'm consuming)
I'm wondering if my beta cells are very damaged and not producing enough insulin (diagnosed for 10 years - and haven't given it a real go until now!) or I am still over my personal fat threshold and my liver and pancreas are clogged up with fat and not functioning properly.
Assuming that Prof Taylor is correct.if a person has true type 2 diabetes, then they have more fat than their beta cells can tolerate.
Evidence please?and in any case will certainly reduce your risk of 13 types of cancer
References pleaseny case will certainly reduce your risk of 13 types of cancer as well as lots of other nasty health conditions you don't want.
https://www.cancerresearchuk.org/ab...-and-cancer/what-are-the-benefits-of-exercise may be the reference meant. Which has nothing to do with managing diabetes or Prof Taylors methods.References please
What is “true” type 2 and conversely what other sorts are there? This is not explained in the articleif a person has true type 2 diabetes
Thank you.https://www.cancerresearchuk.org/ab...-and-cancer/what-are-the-benefits-of-exercise may be the reference meant. Which has nothing to do with managing diabetes or Prof Taylors methods.
Does Body Weight Affect Cancer Risk?References please
Does Body Weight Affect Cancer Risk?
Being overweight or obese is clearly linked to an overall increased risk of cancer. According to research from the American Cancer Society, excess body weight is thought to be responsible for about 11% of cancers in women and about 5% of cancers in men in the United States, as well as about 7% of all cancer deaths.
Being overweight or obese is clearly linked with an increased risk of many types of cancer, including:
Being overweight or obese might also raise the risk of other cancers, such as:
- Breast cancer (in women past menopause)
- Colon and rectal cancer
- Endometrial cancer (cancer of the lining of the uterus)
- Esophagus cancer
- Gallbladder cancer
- Kidney cancer
- Liver cancer
- Ovarian cancer
- Pancreas cancer
- Stomach cancer
- Thyroid cancer
- Multiple myeloma
- Meningioma (a tumor of the lining of the brain and spinal cord)
The link to body weight is stronger for some cancers than for others. For example, excess body weight is thought to be a factor in more than half of all endometrial cancers, whereas it is linked to a smaller portion of other cancers.
- Non-Hodgkin lymphoma
- Male breast cancer
- Cancers of the mouth, throat, and voice box
- Aggressive forms of prostate cancer
https://www.cancer.org/cancer/cance...vity/body-weight-and-cancer-risk/effects.html
https://www.health.harvard.edu/stay...aching-effects-of-a-little-bit-of-weight-loss
Weight loss effects
The most visible sign of weight loss is a slimmer body. But there are many important changes that you cannot see, including any of the following.
Reduced heartburn.
Reduced knee pain
Reduced blood pressure
Reduced diabetes risk
Better sexual function.
Improved sleep
Extra energy.
More self-esteem
opinions, and nothing about blood sugar levels and cancer. Not sure why this is on this thread.Does Body Weight Affect Cancer Risk?
Being overweight or obese is clearly linked to an overall increased risk of cancer. According to research from the American Cancer Society, excess body weight is thought to be responsible for about 11% of cancers in women and about 5% of cancers in men in the United States, as well as about 7% of all cancer deaths.
Being overweight or obese is clearly linked with an increased risk of many types of cancer, including:
Being overweight or obese might also raise the risk of other cancers, such as:
- Breast cancer (in women past menopause)
- Colon and rectal cancer
- Endometrial cancer (cancer of the lining of the uterus)
- Esophagus cancer
- Gallbladder cancer
- Kidney cancer
- Liver cancer
- Ovarian cancer
- Pancreas cancer
- Stomach cancer
- Thyroid cancer
- Multiple myeloma
- Meningioma (a tumor of the lining of the brain and spinal cord)
The link to body weight is stronger for some cancers than for others. For example, excess body weight is thought to be a factor in more than half of all endometrial cancers, whereas it is linked to a smaller portion of other cancers.
- Non-Hodgkin lymphoma
- Male breast cancer
- Cancers of the mouth, throat, and voice box
- Aggressive forms of prostate cancer
https://www.cancer.org/cancer/cance...vity/body-weight-and-cancer-risk/effects.html
https://www.health.harvard.edu/stay...aching-effects-of-a-little-bit-of-weight-loss
Weight loss effects
The most visible sign of weight loss is a slimmer body. But there are many important changes that you cannot see, including any of the following.
Reduced heartburn.
Reduced knee pain
Reduced blood pressure
Reduced diabetes risk
Better sexual function.
Improved sleep
Extra energy.
More self-esteem
“Substantial weight loss achieved by any means can bring about remission of type 2 diabetes”, not just vlc. I have often cited this statement by Prof Taylor, which he has made several times. It really doesn't matter at all what diet you use to lower your calorie intake as long as you eat fewer calories than you use. He has also said that the reason he himself prefers the vlc diet is that people tend to be better able to stick to it for long enough to lose sufficient weight, whereas they might give up slower diets before they have lost the ideal 15% of their original weight. I myself use a low, not very low, calorie diet of 1000 cals per day. It has been working for me. Very low is defined as 600 to 800 cals. As to only carbs causing raised triglycerides that is not true. ANY macronutrient eaten to excess, in excess of the person's daily calorie expenditure will get turned into triglycerides in the body.What is “true” type 2 and conversely what other sorts are there? This is not explained in the article
Reading your link early on there is this paragraph that leaves me asking questions “The twin cycle hypothesis: during long-term intake of more calories than are expended each day, excess carbohydrate must undergo de novo lipogenesis, which particularly promotes fat accumulation in the liver. As insulin stimulates de novo lipogenesis, people with insulin resistance (determined by family or lifestyle factors) will accumulate liver fat more readily than others due to the higher plasma insulin levels.” First is that it identifies excess carbs cause the issue of fat accumulation, not excess calories or excess fat or excess protein. The second is this and the diagram it refers to talk about preexisting insulin resistance as the initial trigger to this fat accumulation. Where does this IR come from and how about addressing that? The only answer seems to be “Many people have fatty liver disease and raised plasma triglyceride, but only a proportion of these go on to develop type 2 diabetes. Detailed genetic studies are required to define the basis of the evident degrees of susceptibility in different individuals”
I also note the quote “Substantial weight loss achieved by any means can bring about remission of type 2 diabetes” not just vlc
And also “Independently, insight has been gained into the biology of return of insulin secretory capacity after decrease in exposure of beta cell to deleterious levels of triglyceride”. Interestingly very low carb almost always significantly reduces trigs so would also generate the same benefits of this reduction. It seems there’s more than one way to achieve the same results.
Is there a follow up as suggested “The personal fat threshold concept is immediately understandable by patients as a way of explaining their condition and the way forward. As a hypothesis it requires experimental verification, and a study is in progress.”
I’m left with as many questions as answers.
“Substantial weight loss achieved by any means can bring about remission of type 2 diabetes”, not just vlc. I have often cited this statement by Prof Taylor, which he has made several times. It really doesn't matter at all what diet you use to lower your calorie intake as long as you eat fewer calories than you use. He has also said that the reason he himself prefers the vlc diet is that people tend to be better able to stick to it for long enough to lose sufficient weight, whereas they might give up slower diets before they have lost the ideal 15% of their original weight. I myself use a low, not very low, calorie diet of 1000 cals per day. It has been working for me. Very low is defined as 600 to 800 cals. As to only carbs causing raised triglycerides that is not true. ANY macronutrient eaten to excess, in excess of the person's daily calorie expenditure will get turned into triglycerides in the body.
· "What are triglycerides? Triglycerides are a type of fat. They enter your blood when: • extra calories that you eat are not used for energy. • you eat excess fat in your diet. • they are released from the fat already stored in your body. High levels of triglycerides in your blood can increase the chance that you develop heart disease. Triglycerides do not build up in the arteries like bad cholesterol (LDL). Instead, high levels can make LDL cholesterol change into a more harmful form that damages the arteries. High triglycerides also keep you from forming good cholesterol (HDL). If triglycerides are very high, a dangerous condition called “pancreatitis” (inflammation in the pancreas), can develop." https://www.uwhealth.org/healthfacts/nutrition/361.pdf
↑Assuming that Prof Taylor is correct.
This is a theory not a fact however many times you state it as thought it is. And it is fat around the pancreas causing the problem not "beta cells" per se.
Evidence please?
This is certainly a new one on me...
As long as you lose weight is what prof Taylor says and I quoted. You have added bit about a calorie deficit. That is your interpretation. He has a preference for one method. Other people have a preference for others. If his theory is right it doesn’t matter how so long as there is weight loss. Your claim that low carb is slower is based on what evidence? Still waiting on any studies that explain what to do about the significant minority that do not have 15kg to lose btw and how his theory will accommodate them. The crux of it is his theory applies to some type 2, not all.as long as you eat fewer calories than you use
that is not what I said nor quoted. What I quoted was actually about carbs causing fat in the organs and then a separate quote about triglycerides and their effect on beta cells. You merged the two separate issues.As to only carbs causing raised triglycerides
As long as you lose weight is what prof Taylor says and I quoted. You have added bit about a calorie deficit. That is your interpretation. He has a preference for one method. Other people have a preference for others. If his theory is right it doesn’t matter how so long as there is weight loss. Your claim that low carb is slower is based on what evidence? Still waiting on any studies that explain what to do about the significant minority that do not have 15kg to lose btw and how his theory will accommodate them. The crux of it is his theory applies to some type 2, not all.
that is not what I said nor quoted. What I quoted was actually about carbs causing fat in the organs and then a separate quote about triglycerides and their effect on beta cells. You merged the two separate issues.
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