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Vitamin C can reduce Bg levels ?

Discussion in 'Alternative Treatments' started by Soundgen, Nov 6, 2009.

  1. Soundgen

    Soundgen · Well-Known Member

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  2. Soundgen

    Soundgen · Well-Known Member

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    Another interesting link presumably of interest to Type 1s and Type 2s who have progressed to Insulin use

    elements4health.com/researchers-stop-diabetes-damage-with-vitamin-c.html
     
  3. Soundgen

    Soundgen · Well-Known Member

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  4. Soundgen

    Soundgen · Well-Known Member

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    newswithviews.com/Howenstine/james52.htm
     
  5. Soundgen

    Soundgen · Well-Known Member

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    Put in an airy fairy sideing
     
  6. cugila

    cugila · Master

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    Soundgen.

    Airy Fairy....I don't think the previous posters in this area would think of their subjects in such a way. Just tidying up and moving posts to the correct areas. It is an ongoing process.
     
  7. Patch

    Patch Type 2 · Well-Known Member

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    This needs more discussion...

    Soundgen - my own research has led me to Vitamin C. Very interesting that Vitamin C and Insulin share the same mechanism for getting into cells.

    I've been experimenting with my dosage of Vitamin C and have been up as high as 7000mg in a day (I take 2 1000mg effervescent tablets and 1tsp (5000mg) ascorbic acid in 750ml of water).

    Interesting to see that the above study found significant results with 1g doses.

    I think that even the study that show a negative impact on BG is helpful. At least it points to a link between Vitamin C intake and BG levels. It's perfectly reasonable to think that a dose of 1g could be beneficial, and a dose of 4g+ could be detrimental...
     
  8. catherinecherub

    catherinecherub · Guest

  9. phraedus

    phraedus · Active Member

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    .comparativeguide.com/index.php?option=com_content&view=article&id=7&Itemid=8
     
  10. phraedus

    phraedus · Active Member

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    (Blog content and link removed. Forum Policy.)

    http://www.newmediaexplorer.org/sepp/Di ... _Singh.pdf
     
  11. cugila

    cugila · Master

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    http://www.netdoctor.co.uk/dietandnutri ... tamins.htm

     
  12. jaykay

    jaykay · Well-Known Member

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    I condense the above post to one line : An apple a day keeps the doctor away :D . I shall stick with my apple!
     
  13. phraedus

    phraedus · Active Member

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    http://en.wikipedia.org/wiki/Diabetic_n ... ol_pathway

    Vitamin c is the most efficacious inhibitor of aldose reductase that is known to my understanding the only other inhibitors are fenofibrates (sp) for triglycerides.
     
  14. cugila

    cugila · Master

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    Glad to hear it J.......All the previous ones just seem to be promoting the use of supplements, makes you wonder what the aim is.....selling perhaps ??

    Merry Christmas BTW......... :D

    I only popped in to see what was happening........ :twisted:
     
  15. phraedus

    phraedus · Active Member

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    http://www.newmediaexplorer.org/sepp/Di ... _Singh.pdf
     
  16. cugila

    cugila · Master

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    All very interesting dear phraedus........do you have a voice of your own perhaps so that us poor mortals can see what you are trying to prove........ :?: You seem pre-occupied with posting other peoples works. Very reminiscent of someone else we know...... :wink:
     
  17. phraedus

    phraedus · Active Member

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    I'm a 58 yr old retired 6yr diabetic ; I spend most of my day googling diabetes. Its sort of turned into a hobby for me during the winter months.

    I found this flow diagram:

    [​IMG]

    http://care.diabetesjournals.org/conten ... l.pdf+html

    I basically use it as a template for researching the neuropathies and the hows and whys of them occurring due to hyperglycemia; if I find something interesting I post to a couple of forums.

    Just a newbie to diabetes .co.uk still learning the ins and outs of what is allowed

    Cheers :D
     
  18. cugila

    cugila · Master

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    Glad to hear you are into research.....what we do here all the time, into all sorts of things. Maybe you could put some of what you have found into laymans terms.....you might find people are more receptive when it isn't all techo stuff without any expalnation ?

    Anyway, it's late. It's Christmas........
     
  19. phraedus

    phraedus · Active Member

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    The polyol pathway: The first Horseman of Neuropathy.Also called the sorbitol-aldose reductase pathway.

    When there is an excess of glucose in the retinal renal or nerve cell the conversion of glucose goes to sorbitol and then to fructose all is well.\???

    As the cell uses the glucose for energy production any excess glucose is diverted to the polyol pathway ; if the mass balance of the equation becomes overwhelmed conversion stops at sorbitol.

    Excess sorbitol in the cytoplasm of the cell is detrimental sorbitol scavenges water and swells the cell causing apotosis (cell death).

    Vitamin c scavenges sorbitol and rids it from the body it is also an aldose reductase inhibitor so it slows down production of sorbitol as well.

    The reason I supplement with vitamin c is that vit c is insulin dependent it uses the same pathway as insulin to enter the cell. However this line of reasoning may be in error retinal renal nerve and endothelial cells do not use insulin they use glut1 which is not insulin dependent this is the reason these cells are affected by the hyperclycemic condition and the rest of the body is not perhaps an apple a day is all it takes, as for me I will keep supplementing.

    Merry Christmas and Happy New Year to et al.
     
  20. phraedus

    phraedus · Active Member

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    http://jasn.asnjournals.org/content/14/ ... /S233.full

    [​IMG]

    AGE. The second Horseman of Neuropathey. Also known as Advanced Glycation End products

    As you can see from the flow diagram the polyol pathway is going to completion to fructose this is feeding back as a toxic metabolite into the remaining pathways to diabetic complication vit c is still good though because it is reducing frucose as an aldose reductase inhibitor and also assisting if the conversion stops at sorbitol.

    [​IMG]

    http://www.uninet.edu/cin2003/conf/thor ... alley.html

    http://www2.warwick.ac.uk/newsandevents ... d_vitamin/

    The second diagram is known as the PPP pentose phosphate pathway it is regulated by thiamine status if you are deficient in thiamine you will not access this pathway now it is your own personal decision whether to supplement with thiamine or not.

    Cheers :?:
     
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