I am very worried about my diabetic tablets (i.e. metformin 1,000 mg) BD & blood pressure tablets (i.e. Losartan, istadipine, indapamide) contains Titanium dioxide which I gather from several websites that titanium dioxide nano-particles (NP) are absorbed in the intestines & blood-brain barrier causing oxidative stress and necrosis to in glial cells & neurones in the brain. I am extremely worried about the possibly (however slight) of necrosis (cell death) to the glial cells & neurones in the brain - enough to greatly worry & stress me every second of my waking moments. I know some foodstuffs (& cosmetics, sunscreens, etc) contain Titanium dioxide but I can read the labels before buying them. As for prescribed drugs medication obtained from a pharmacy this is more problematic. Is there such tablets without titanium dioxide as a inactive (colouring)agent? Are there possible tablets & pharmaceutical retailers I approach on this matter (so that I can sent my repeat prescriptions to them to dispense.