Can Metformin HCL 1000mg cause vitamin B12 deficiency?
- Thread starter cmx9
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Your GP is wrong.
Copied from the leaflet (https://www.geneesmiddeleninformatiebank.nl/bijsluiters/h128396_piluk.pdf):
Common (may affect up to 1 in 10 people) • changes in taste • decreased or low vitamin B12 levels in the blood (symptoms may include extreme tiredness (fatigue), a sore and red tongue (glossitis), pins and needles (paraesthesia) or pale or yellow skin). Your doctor may arrange some tests to find out the cause of your symptoms because some of these may also be caused by diabetes or due to other unrelated health problems.
Instead of buying a testing kit (no idea if this is possible), I'd show him the leaflet and ask for B12 to be included in your next blood test.
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I was on Metformin for some years and B12 levels weren’t routinely tested for, however I asked my GP for them to be included in my annual bloods a couple of times, which he agreed to. Why should you have to pay, when it is a known problem with Metformin?
I bought a home test for B12 as I had burning tongue syndrome. The results were that I wasn't deficient. I told my GP and he said the tests you buy for B12 aren't always reliable. He did another which did indeed show a deficiency.
So yes, metformin can deplete your B12 levels and no, I wouldn't waste money on buying your own test.
So yes, metformin can deplete your B12 levels and no, I wouldn't waste money on buying your own test.
It is very very well documented that Metformin depletes B12, and even iron and calcium. Supplementation with calcium is not recommended unless the doctor recommends to do so. It’s complicated. Supplementing with iron would probably only matter if you are vegetarian or vegan. B12 supplementation also depends on these factors. If you are older or don’t eat meat, you will almost definitely need B12. It’s vital. I get tested for B12 every time I do bloods. It comes with Folate or without. Not everyone needs Folate, ask dr again. Dr’s are there to help sick people not to keep us well. Thats the sad and wrong part in this World. The self care is up to us. Learn as much as you can about your own disease and be as active as you can in getting opinions of others who have this attitude. Which is what you’re doing now and thats great!
Crazy! Several doctors have agreed with me on the B12 and tested and found without supplementation, B12 is too low. Neuropathy gets very bad without B12 if I don’t supplement and energy too. I’m amazed! Now my doctors recommend B12. Get another doctor! You’s sounds bad.
I started on Metformin in August last year and even after 3 month my B12 had reduced. My doctor included it automatically in the blood panel. So I take a supplement now. I have my next blood panel in two weeks. Curious how my body is doing in general, but I was surprised that B12 reduction - no real deficiency yet - showed up so quickly as most sources talk more long term impact.
Be aware that the NHS level of "acceptable" B12 levels is on the low side. If we supplement, any that the body doesn't need is excreted harmlessly, unlike such things as iron.
I have been on 1000mg metformin twice daily (told to take with food) since I was diagnosed with type 2 in 2006. I don't know if the metformin had anything to do with my low B12, or if it was something to do with my diet, or the many medications I take to control my myeloma.
Just recently I was asked to repeat a routine blood test to confirm that my B12 was within acceptable levels. Having had the blood test I received a text from my GP practice stating my B12 was rather on the lower end to spectrum, and I love this bit, "you are not eating enough red meat, or drinking enough milk"!
I love red meat and I drink milk almost by the gallon. When I read the text to my wife, she nearly fell to the floor in hysterics.
The serious part of this for me, was that I was unaware low consumption of red meat and milk could have this affect on my B12 levels. I know taking a B12 supplement.
Just recently I was asked to repeat a routine blood test to confirm that my B12 was within acceptable levels. Having had the blood test I received a text from my GP practice stating my B12 was rather on the lower end to spectrum, and I love this bit, "you are not eating enough red meat, or drinking enough milk"!
I love red meat and I drink milk almost by the gallon. When I read the text to my wife, she nearly fell to the floor in hysterics.The serious part of this for me, was that I was unaware low consumption of red meat and milk could have this affect on my B12 levels. I know taking a B12 supplement.
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This is from the NHS website. It might be useful for your GP.
www.nhs.uk
Side effects of metformin
NHS medicines information on side effects of metformin and what you can do to cope.
www.nhs.uk
Maybe this is american-only problem but diabetics can drink milk? Whenever I drink anything that's not water or a sugar free soda, my blood sugar spikes to 250. Everything we have has added sugar and I'm worn out trying to find foods that aren't actively out to hospitalize me.
I should also say that I'm very poor and that my doctor is the only person I could find close to where I live that does reduced costs for visits. I guess I get what I pay for if he's confident that b12 isn't lowered by metformin. Love american healthcare!
LittleGreyCat
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Diet drinks - the artificial sweeteners taste vile.
Having to forswear foods I have loved all my life.
Trying to find low carb meals when eating out.
Normally yes, depending on the quantity!
There are more carbohydrates in skim milk than full fat milk.
Cream is even lower carbohydrate.
Cheese is also good as some carbohydrate is fermented out during production.
aylalake
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Being told “Oh go on, one won’t hurt you!”.
Conversely, the food police.
Double cream diluted with water makes an acceptable milk substitute. Personally I just use cream full strength but that can get expensive.
jjraak
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Winner for being aware.
Hug for the doctor being so misinformed.
Like others I asked for B12 testing to be added to my blood works ...no problem
Now gets tested each time.
A fair few posts regarding the issue.
I posted this.
I found the lady in question on YouTube not long after finding out how I could be impacted (I was )
I'd recommend anyone over sixty or taking Metformin gave it a moment of their time.
I'd even go so far as saying if they have anyone they love in that category, it's worth the watch of the film I link to.
Good luck finding a doc who understands Metformin properly.
Vitamin B12 confusion
Hi All, I’m hoping some of you will be able to help me understand some recent blood test results I’ve received. I bought a HbA1c test from the shop on this site as I am in need of some motivation to get back on the low carb wagon after an indulgent Christmas. Did the test, posted off, a week...
www.diabetes.co.uk
