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Effects of excess glucose on neurone pathways in the brain.

leslie10152

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I am currently putting some thought into the situation of glucose having a debilitating effect on neurone pathways in the brain, comparable to the effects of nitrogen narcosis. I need some more time to put my theory together. All comments welcome.
 
Are you hypothesising that raised blood sugar within the brain is similar to being stoned or more serious aspects of nitrogen narcosis? I need a bit more such as are we talking normal glucose levels elevated levels or lower levels?
 
I would be interested to understand the relationship between depression/stress and T2. I suffered depression for 12 months before I was diagnosed T2. Could this be due to the increase in glucose and other damaging substances like adrenaline production? Or does the onset of Type2 negatively affect brain function causing depression ? Chicken or the egg dilemma.
 
Having been at one time an advanced BSAC diver I have experience nitrogen narcosis many times but have never experienced similar feelings when my bg levels were high so I would say categorically no.

Although a lack of glucose when bg levels are very low (hypoglycaemia) is very similar with that same feeling of confusion.

Interesting topic.
 
This is my thinking along the op's question.
Through my fight to get my diagnosis, I have had symptoms of really high glucose levels (hyperglycaemia), I have had my fair share of low glucose levels (hypoglycaemia), I have had high insulin (hyperinsulinaemia) and am now resident in ketosis, which is where I like to be! Because of my condition I have also been through the rollercoaster ride of fluctuating blood glucose levels.

Through the many, many papers on the subject of what the symptoms are especially concerning the brain and how these highs and lows affect your well being and how you can really suffer as the symptoms take over!

The symptoms of all the above do effect the brain in so many ways, otherwise how do you get symptoms?
Symptoms are the direct result of the brain's response to a change in any of the body's hormones, so many symptoms are similar wether high or low and up and down constantly.
So, yes! High glucose levels (hypoglycaemia) does effect your pathways and how you feel! Emotional response are natural defences against your hormones.

The chemistry of the balance in your blood varies, but too much of any of your hormones will trigger symptoms.
And what you eat will further disrupt the balance because the trigger of your brain, gut, insulin response is essentially important in keeping your blood glucose levels around normal if you have an metabolic condition.

I can assure you, if nitrogen narcosis is anything like my hypo hell, the symptoms are closely related.
 
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