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<blockquote data-quote="andrewk" data-source="post: 269110" data-attributes="member: 37453"><p>Indeed yes, but if the study team's hypothesis that Type 2 diabetes is caused by excessive fat in the pancreas and liver is true AND if the diet normalises those fat levels then the effect should be permanent, providing of course that a sensible diet is adopted thereafter.</p><p></p><p>I think my main concern is that the presentation of some of the statistics in the study report is a bit icky. A lay-reader could easily be drawn to the conclusion that the fasting BG and HBA1C normalised in the diabetic study group by the end of the 8 week period - but that isn't what the report actually says. It says that they are "not significantly different" from those of the non-diabetic control group, which isn't the same thing at all. Both the diabetic group's mean fasting BG and mean HBA1C were still higher than those of the control group - and that difference might well have been significant if the sample size had been larger.</p><p></p><p>I'm moderately confident that the effect will be permanent, providing that I don't repeat whatever I did to give myself the disease in the first place. I'm also convinced that 8 weeks of drinking pink grot meal replacements is far from the end of the story and that my blood glucose will only be truly normalised after a long period of sensible (low carb) dieting, if ever.</p><p></p><p>I agree with your comment about BMI. To get down to a BMI of say 22, I need to lose another 60 lb which, if achieved, will mean that I'll have lost just short of 8 stones in total. Maintaining motivation for the 6-12 months needed to achieve that could be quite a challenge. (I'll need quite a few new clothes too!!)</p><p></p><p>Andrew</p></blockquote><p></p>
[QUOTE="andrewk, post: 269110, member: 37453"] Indeed yes, but if the study team's hypothesis that Type 2 diabetes is caused by excessive fat in the pancreas and liver is true AND if the diet normalises those fat levels then the effect should be permanent, providing of course that a sensible diet is adopted thereafter. I think my main concern is that the presentation of some of the statistics in the study report is a bit icky. A lay-reader could easily be drawn to the conclusion that the fasting BG and HBA1C normalised in the diabetic study group by the end of the 8 week period - but that isn't what the report actually says. It says that they are "not significantly different" from those of the non-diabetic control group, which isn't the same thing at all. Both the diabetic group's mean fasting BG and mean HBA1C were still higher than those of the control group - and that difference might well have been significant if the sample size had been larger. I'm moderately confident that the effect will be permanent, providing that I don't repeat whatever I did to give myself the disease in the first place. I'm also convinced that 8 weeks of drinking pink grot meal replacements is far from the end of the story and that my blood glucose will only be truly normalised after a long period of sensible (low carb) dieting, if ever. I agree with your comment about BMI. To get down to a BMI of say 22, I need to lose another 60 lb which, if achieved, will mean that I'll have lost just short of 8 stones in total. Maintaining motivation for the 6-12 months needed to achieve that could be quite a challenge. (I'll need quite a few new clothes too!!) Andrew [/QUOTE]
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