For a month, after reading a while about things that theoretically could be good to the pancreas and insulin secretion, I've combined 1800mg of Berberine, 1500mg of Bitter Melon extract, 1 raw garlic clove (5g~9g, very hard to take it), a small piece of Ginger (20g~30g, not that easy either) and a hard to define amount of capsaicin (20~40 drops of Tabasco pepper on food, no idea how much capsaicin that is).
My average FBG dropped about 7,75%, from 96,37 mg/dL to 88,9 mg/dL (this is average, on some days I'd have
108mg/dL, for instance, I am a prediabetic). During this month, I ate freely, there was good food, but also junk and chocolate and many other stuff. I've tried many diets for over a year, I just couldn't handle always having something forbidden anymore, specially because my BG was slowly rising no matter what I did and how disciplined I was. I've tried from full vegetarian to carnivore, from 16-hour fasting every day to 7-day fasting twice (3 months distance between each 7-day fasting).
With all those things I'm still taking (berberine/bitter melon/garlic/ginger/pepper), one thing I simply cannot understand is that now usually when I eat more sugar, the next day I have lower FBG. I've never experienced anything like that before. I take no medication. So, for instance, I've been getting better FBG the day after I eat 100g of chocolate than the day after I eat 50g, On a particular day I ate rice and potatoes, no candies at all, and I was surprised my next FBG was
higher than the values I'd get after chocolate days!
I've decided to try something related to pancreas and β cells simply because my HOMA-IR index (1,00) and HOMA-β index (44,26) implied (just implied, I know those indexes have limitations) I don't seem to have an IR big issue but I do seem to have an impaired insulin secretion all right.
I am a lean pre-diabetic and I still haven't tried traditional medication for treating diabetes.
If anyone's interested, a few links on the things I've tried:
Berberine:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2410097/
Bitter Melon
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4027280/
Garlic
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642189/
Ginger
https://www.intechopen.com/books/gi...view-of-the-antidiabetic-activities-of-ginger
Capsaicin
https://pubmed.ncbi.nlm.nih.gov/28230360/