Sean_Raymond
Well-Known Member
- Messages
- 78
- Type of diabetes
- HCP
If there are any that spring to mind feel free to post it although I appreciate it may be unreasonable to ask. I'd genuinely like to see solid evidence that reducing circulating insulin (independent of calories) causes weight loss.His book has over 30 pages of references..
Excellent. I'll have a look at that link! Thank you.There are studies that show this happens without a calorie deficit just the carb reduction. I’ve posted them before. I’ll try and find them again.
possibly these might answer some of the points. Not sure if the one I’m thinking of specifically is there
https://www.diabetes.co.uk/forum/th...-treating-diabetes.178134/page-8#post-2337293
If there are any that spring to mind feel free to post it although I appreciate it may be unreasonable to ask. I'd genuinely like to see solid evidence that reducing circulating insulin (independent of calories) causes weight loss.
Well we know that lack of circulating insulin usually leads to weight loss.. you just need to check with many T1's for whom one of the main leads for diagnosis was unexpected weight loss however much they ate.
I have never seen this as a definition of calorie deficit. I have only seen it referring to intake, not ability to utilise. This definition does fit your arguments far better than the usual one does though.he weight loss could essentially be said to also be the result of a calorie deficit because much of the dietary energy isn't being used and or excreted out.
Is this the sort of thing you mean?Why don't you show me one controlled study showing insulin reduction causes weight loss. Just one.
Disagreement isn't hostility. Such comments are often used to try to make someone back down.You seem hostile for some reason.
May I have links to studies showing this please?insulin itself isn't the cause of weight gain/adiposity and reducing its levels per se will not be the reason a person loses weight.
Which is how I eat.although animal foods would likely have made up the majority of the diet for various hunter gathered tribes.
Why don't you get Ben's book and read it?Why don't you show me one controlled study showing insulin reduction causes weight loss. Just one.
edited by moderator
Not a definition, just an explanation. In the case of weight loss that may be seen prior to a type 1 diabetes diagnosis we have a few things happening. Most people will presumably be eating a diet where carbohydrate provides a substantial % of their energy intake. The lack of insulin means they are essentially in a calorie deficit because they are unable to fully access that dietary energy. Energy is also likely being lost in the urine and they may have slightly higher energy expenditure because the lack of insulin is unable to shut down endogenous glucose production in the liver (gluconeogenesis etc) which itself exacerbates loss of body tissue.I have never seen this as a definition of calorie deficit. I have only seen it referring to intake, not ability to utilise. This definition does fit your arguments far better than the usual one does though.
Thank you for showing me this. I appreciate that weight loss wasn't the goal of the researchers however they used diets ranging from 6% CHO to 57% CHO matched for energy and protein and we saw no difference in weight loss so what does that tell you. The actual metabolic findings are interesting however the study is by Jeff Volek who is very invested in the idea that insulin is a cause of obesity and it is funded by low CHO groups. Whilst I cannot comment on their sincerity such a clear position needs to be considered.https://www.sciencedaily.com/releases/2019/06/190620100036.htm.
Low-carb diet may reduce diabetes risk independent of weight loss: Researchers report reversal of metabolic syndrome in some cases
The study clearly states that there was a reduction in calorie intake. This explains the weight loss not the reduction in circulating insulin.Is this the sort of thing you mean?
Suppression of insulin secretion is associated with weight loss and altered macronutrient intake and preference in a subset of obese adults - PubMed (nih.gov)
Suppression of insulin secretion is associated with weight loss and altered macronutrient intake and preference in a subset of obese adults. - Abstract - Europe PMC
Certainly. Let me know what you think of these.May I have links to studies showing this please?
Or for purposes of this discussion, perhaps just cite the evidence to support your claim.Why don't you get Ben's book and read it?
With 30 pages of references the book, written by an expert by the way, is a far better source of information than I can provide you with.Or for purposes of this discussion, perhaps just cite the evidence to support your claim.
Certainly. Let me know what you think of these.
https://pubmed.ncbi.nlm.nih.gov/27385608/
4 weeks.. hardly time to get into deep nutritional ketosis and certainly not long enough to become fat adapted..
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603544/
6 days.. seriously?
https://pubmed.ncbi.nlm.nih.gov/29466592/
Not really a controlled study of low carb diets
https://onlinelibrary.wiley.com/doi/full/10.1038/oby.2004.278
4 female participants and apparently no significant difference in weight loss.. hmmm looks like quite a difference to me even after only 6 weeks.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2780863/
Low carb diet with bread and potatoes.. ok doesn't sound very low carb to me..
(PDF) Fat and carbohydrate overfeeding in humans: Different effects on energy storage (researchgate.net)
Seems to show that even short term in the healthy and obese carbs raise insulin secretion levels will minimal impact on blood glucose levels. ? Still only over 2 weeks though.
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