jpscloud
Well-Known Member
- Messages
- 820
- Type of diabetes
- Type 2
- Treatment type
- Tablets (oral)
I am reading on ketone metabolism and I come across this. These caught my attention. It generates free radicals. During non fasted and carb limited time, our livers also produce Keynes.
https://www.diapedia.org/metabolism-and-hormones/51040851169/ketone-body-metabolism
Ketone bodies stimulate insulin release in vitro, generate oxygen radicals and cause lipid peroxidation. Lipid peroxidation and the generation of oxygen radicals may play a role in vascular disease in diabetes[2].
Your quoted extract is taken from tbe section entitled Ketoacidosis, and refers to that condition, I think - out of context as we are discussing nutritional ketosis?
Sorry, not entitled Ketoacidosis, but exclusively concerning that.
I should take more time when posting Your quoted extract concerns abnormally high levels of ketones, at the opposite end of the scale from nutritional ketosis.
And yet another edit: So the role that lipid peroxidation and the generation of oxygen radicals may play in vascular disease in diabetes is probably dependent on the levels of ketone bodies seen in uncontrolled diabetes, in the condition of ketoacidosis... at least this is how it seems to me.
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