I've had diabetes for more than 25 years. I am always changing my eating habits, and take my insulin shortly before my meals in most instances, and always circulate my injection locations (short-term in stomach, long-term in butt). For the past few months my morning insulin doses have not been "kicking in" within 10-15 minutes like they are supposed to, but instead take 2-3 hours. I wake up, take my insulin, eat my breakfast (which varies - and yes, I take the appropriate amount based on carb intake). An hour or more later, my blood sugar spikes (based on the amount of carbs, but typically to 19-20's mmol/L = 360 mg/dl) as though I didn't take any insulin at all. Then finally - up to 3 hours later - the insulin kicks in and drops me back down to the appropriate level based on the dosage I took for my breakfast. Has anyone experienced this before? I am very concerned and my doctor and endocrinologist don't seem to have a solution for the problem (besides changing injection locations or insulin types, both of which I have done). Odder still, later in the day, my insulin kicks in as normal, within 10-15 minutes after injection, like nothing is wrong. Most injections I take before lunch (if more than one) take 2-3 hours to react. So frustrating! Any thoughts are welcome!