Hi AA,
When one takes an ARB it tends not to produce the cough. ARBs work further down the chain on angiotensin 2.
Reducing sodium intake increases renin and if not regulated constricts arteries increases aldosterone. Hence need for ARBs etc.
If sodium intake is low, Aldosterone should not cause end organ damage.
It is all very complex ... homeostasis of bp etc.
I have Conn's syndrome and have an adrenal tumour producing 20x the normal amount of aldosterone. We leak potassium due excess aldosterone.
This also prevents pancreas working properly when potassium is lost from tissue.
The only way to stop organ damage, which has already occurred, is to reduce sodium intake, but that increases aldosterone further.
Hence my need for an ARBs and Aldosterone receptor blockers.
I'll put your article to the Conn's group I am on. Thanks.
D.