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Metformin side effects

S

SarahMarie

Member
Hi everyone I was diagnosed a week before Christmas and was immediately put onto Metformin 500mg, I was told to take one tablet each day for 7 days and then increase the dosage to one tablet twice per day. I was warned that if the side effects were awful then I could be switched to slow release tablets. Well that first week the side effects were awful, I had full blown diarrhoea at least 4 or 5 times per day with very little warning beforehand. I persevered for almost 7 days before phoning my GP in tears and begging to be put on to the slow release. My GP agreed and I was instructed to start again with one slow release tablet per day for 7 days before increasing the dosage to one tablet twice per day. The side effects instantly reduced and thankfully I wasn’t rushing to the toilet multiple times per day.

The thing is, I’ve now been on the slow release tablets for 7 weeks and I’m still suffering at least 5 times per week with sudden diarrhoea usually late at night. Is it the metformin? Is it likely to settle down? Is there anything I can do to try and stop it? Could it be foods that are interacting with it?

Thanks for reading and sorry for the essay
 
Hi. I agree that everyone should be put onto the SR version of Metformin from the start as I was. It only costs a little bit more but it does avoid most symptoms for many. Sadly NICE doesn't say that. There are some who can't tolerate either version and as it only reduces BS a small amount I would discuss stopping it with the GP.
 
My Hba1c was 53 and was diagnosed type 2. It’s just that 7 weeks in I’m still suffering once a day at least 5 times per week. Obviously I’m pleased that the side effects are nothing like what they were originally but it’s still driving me nuts
 
Hi @SarahMarie and welcome to the forum!
Have you addressed your diet as well? I ask for two reasons. Firstly Metformin will not control blood sugars by itself and secondly because I’ve heard that in some people the side effects are worse if you continue to eat high carb meals, lowering your carbs will help control your diabetes too.
 
Rachox said:
Hi @SarahMarie and welcome to the forum!
Have you addressed your diet as well? I ask for two reasons. Firstly Metformin will not control blood sugars by itself and secondly because I’ve heard that in some people the side effects are worse if you continue to eat high carb meals, lowering your carbs will help control your diabetes.
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Thank you, I started following and attending SlimmingWorld in October, we went to zoom meetings in November when Greater Manchester went into tier 3 and as of tonight I’ve lost 1.5stone. I eat a lot of meat and veg daily, pasta/rice maybe once per week, bread/cereals once per day, potatoes several times per week. Milk/cheese/fruit daily. I’ve cut back loads on the sweets and chocolate since my diagnosis and maybe have twice per week max
 
A lot of us have success in losing weight and controlling our diabetes by eating only a very small amount of carbs, so it might be worth trying to cut out all pasta, rice, bread, potatoes and cereals, it may also solve the side effects from Metformin too.
 
Rachox said:
A lot of us have success in losing weight and controlling our diabetes by eating only a very small amount of carbs, so it might be worth trying to cut out all pasta, rice, bread, potatoes and cereals, it may also solve the side effects from Metformin too.
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I’ll give it a whirl thanks for the advice, my initial info when I was diagnosed was pretty rubbish so trying to figure a lot of it out myself
 
Mike d said:
As I expected ... lousy diet plan and you weren't to even know it.

Most fruits are full of sugars, pasta / rice, bread, cereals, potatoes full of carbs which are in effect, sugars once digested. Redo required.
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I did ask when I was diagnosed if I now needed to eliminate sugar and was told to reduce my intake of refined sugars (which I have) and also to limit my intake of starchy carbs which again I have done. I tend to have a baked potato alongside a meat dish around 4 times per week. I will have pasta or rice once per week and then either oats or wholemeal toast daily for breakfast. So not actually that much starchy carbs but maybe I need to rethink again. I’ll try cutting out all kinds of sugar/carbs but I’m worried it won’t be sustainable long term. Thanks for the advice
 
I reacted very badly to Metformin, and to the Atorvastatin prescribed with it. I just stopped taking them. They made life unbearable.
I had eaten low carb since diagnosis, so I was getting normal blood glucose levels.
Perhaps you could ask for a reprieve and see how your Hba1c is at your next test - though it would be wise to limit your carbs from now on. You will most likely be seeing high numbers eating those dense carb foods.
 
Poor thing! I suffered similarly with metformin, despite being put on the slow release variety. Talk to your GP surgery as soon as possible. I suffered for months and in the end my whole life was affected by the side effects. There are other medications. Try the low carb, it really works.
 
Providence 62 said:
Poor thing! I suffered similarly with metformin, despite being put on the slow release variety. Talk to your GP surgery as soon as possible. I suffered for months and in the end my whole life was affected by the side effects. There are other medications. Try the low carb, it really works.
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All agreed, for many Metformin has no issues or the issues pass but for some it doesn't, and you shouldn't live with it not improving as there are alternatives with diet and other drugs if needed. Why live in misery?
 
I couldn't tolerate either types so I understand where you're coming from. Go low carb under 30g a day and see how that goes. Very best of luck. Its a real roller coaster being new to all this.
 
Thanks for the reply but I don't know what to eat. I hate most vegetables and salad. I couldn't stomach a cooked breakfast. Really struggling
 
Mike d said:
@SarahMarie .... you're in far safer hands with this forum's advice than you'll ever be with SW.

Oats and toast (of any colour) are really bad for so many T2s I can't begin to count. Milk? No. Thick clotted cream? Yes

Eggs, bacon, great. Yogurt? Same.
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Hi @SarahMarie @Mike d is completely correct. I followed the advice to eat oatmeal with a banana and semi skimmed milk from an NHS nutritionist and my BG level went up like a SpaceX rocket to 11.5+ mmol.

By introducing lo carb (but not to the extent of a Trappist monk's purity) I am now tracking normal BG levels by and large...

We are all different where some can tolerate toast etc no probs at all..but my carb tolerance is as useful as a chocolate fireguard...

All the best!
 
@FIGARO5
I didn't see any question from you, so puzzled as to why you thank somebody for a reply.
If you hate veg (and even fruit) then you can still go Low Carb by going carnivore or modified carnivore (i.e. by eating eggs & full fat dairy as well as meat & fish). The minimum amount of carbs required per day is actually ZERO ! But unless you eat liver (or liver pate) you may need to use vitamin supplements on zero carbs.
Do you like nuts? Most nuts are low carb ( peanuts, cashews and some others have a little more carbs than most). I eat Macadamia, Brazil, Walnut, Almond, Hazelnut.
 
FIGARO5 said:
Thanks for the reply but I don't know what to eat. I hate most vegetables and salad. I couldn't stomach a cooked breakfast. Really struggling
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Same here, although I do like all veggies. Can't do low carb for long as it is so limiting, and I don't really feel it's healthy to exclude so many things.
 
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