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Metformin - when to take it?

Discussion in 'Metformin/Biguanides' started by Alexandra100, Feb 8, 2018.

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  1. Alexandra100

    Alexandra100 Prefer not to say · Well-Known Member

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    I have long wished to try Metformin, and today I managed to persuade my GP to prescribe it for me. She has given me 500mg tablets to take once daily. They are not delayed release. She suggested I cut them in half, but the patient leaflet advises taking them whole. So should I go against the leaflet and try to cut the tablets in half, or should I just take them once a day? And if the latter, WHEN? I would appreciate any advice.
     
  2. Guzzler

    Guzzler Type 2 · Master

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    Take with food and follow your doctor's advice.
     
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  3. Alexandra100

    Alexandra100 Prefer not to say · Well-Known Member

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    Yes, I intend to take it with food, but my doctor gave me no advice as to which meal to take it with, or at what time of day, in the event that cutting the pills in half doesn't work.
     
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  4. Mike D

    Mike D Type 2 · Expert

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    Don't cut them. The drug distribution is different
     
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  5. Tipetoo

    Tipetoo Type 2 · Expert

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    I take mine at breakfast and evening meal times.

    Not sure about cutting them in half though.
     
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  6. Alexandra100

    Alexandra100 Prefer not to say · Well-Known Member

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    Yes, I agree I'd best not cut them. But what do you mean by, "The drug distribution is different"?
     
  7. Rachox

    Rachox Type 2 (in remission!) · Moderator
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    I agree don’t cut them, even if they’re not slow release, the absorption will be affected if you cut them. I’m on 3 x Metformin per day. I started gradually by taking one a week for the first week. I took it whole with my breakfast each day.
     
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  8. Alexandra100

    Alexandra100 Prefer not to say · Well-Known Member

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    Thanks, yes, that sounds like a good plan, it's a shame the manufacturers haven't made lower dose tablets available, especially given the digestive problems people have when starting to take them.
     
  9. Alexandra100

    Alexandra100 Prefer not to say · Well-Known Member

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    I think you must have meant, one a day?
     
  10. Rachox

    Rachox Type 2 (in remission!) · Moderator
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    I did! My bad! Sorry!
     
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  11. knoxy55

    knoxy55 Type 2 · Active Member

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    My diabetic nurse recommends to take at your evening meal. I was taking 1 tablet in the morning, but since taking it in the evening I have managed to bring my count down from 55 to 44.
     
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  12. Guzzler

    Guzzler Type 2 · Master

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    Taking the full tablet per day surely means that you will run out of tablets before your next prescription is due? Unless the doc has put enough on the script to last you one month at one full pill per day (my prescriptions are bi monthly, yours may be different).
     
  13. Tipetoo

    Tipetoo Type 2 · Expert

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    I take two Metformin a day, as there is sixty tablet in the box. I can get a repeat script after twenty days.
     
  14. Guzzler

    Guzzler Type 2 · Master

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    I can order a repeat a few days before I run out but not one/two weeks before, whether I order online or over the phone.
     
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  15. Tipetoo

    Tipetoo Type 2 · Expert

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    I already have the repeats in hand, when my GP writes a script out he ticks the repeat box and enters five.

    It is now a lot easier keeping track of how many scripts I have left, as I use MedAdvisor phone app where the pharmacy enters them into.
     
  16. Rachox

    Rachox Type 2 (in remission!) · Moderator
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    Oh I read it that she was to take one a day but the dr was suggesting half twice a day?
     
  17. Guzzler

    Guzzler Type 2 · Master

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    I read it as half of a tablet per day?
     
  18. Rachox

    Rachox Type 2 (in remission!) · Moderator
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    Alexandra will have to enlighten us!
     
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  19. Mike D

    Mike D Type 2 · Expert

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    The drug in the pill is not distributed 50 /50 after the cut Learnt that one recently :) You'd think so, but not the case
     
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  20. LittleGreyCat

    LittleGreyCat Type 2 · Well-Known Member

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    Most pills have a coating which controls how quickly the drug is absorbed.
    The slow release ones have a different coating which makes them even more slowly absorbed.
    Cutting the pill in half can make it absorb more quickly because there is no coating on the cut part..
    For really fast absorption you are usually given a powder.
     
    • Agree Agree x 1
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