Thanks everyone for your helpful replies. My GP is very aware of the problems many people have on Metformin, so her idea was to start on the lowest possible dose and work up gradually. The
pills I have been given are domed and I don't fancy my chances cutting them in half, so I am starting on 500mg with food and hoping for the best. I finally decided to take the pill with lunch, partly because at breakfast I already take Flecainide x 2 plus Fuoresemide x 2 plus Dabigatran (which can also cause stomach problems).