Type 1'stars R Us

[Hopeful34]

When I was tested I was making no insulin and I have been a type 1 for 22 years, but I think my pancreas still tries

Lows all night are frustrating and tiring @Marie 2 Hope you had a better night last night. I remember reading an article (sorry I don't know where) on insulin production in type I, which showed that even many decades after diagnosis, they could/did periodically produce some insulin. I've often said I was sure my pancreas does at times.

 

[becca59]

Lows all night are frustrating and tiring @Marie 2 Hope you had a better night last night. I remember reading an article (sorry I don't know where) on insulin production in type I, which showed that even many decades after diagnosis, they could/did periodically produce some insulin. I've often said I was sure my pancreas does at times.

I agree. Every few weeks in my case. My Libre results show the struggles of adjusting.

 

[Antje77]

Lows all night are frustrating and tiring @Marie 2 Hope you had a better night last night. I remember reading an article (sorry I don't know where) on insulin production in type I, which showed that even many decades after diagnosis, they could/did periodically produce some insulin. I've often said I was sure my pancreas does at times.

I seem to remember that @EllieM shared that article, can't find it myself at he moment.

 

[EllieM]

I seem to remember that @EllieM shared that article, can't find it myself at he moment.

Could be this one https://pubmed.ncbi.nlm.nih.gov/25519449/
(Has a fascinating scatter graph of insulin production versus length of dagnosis)
but possibly the Scottish one where they found that some long term T1s were actually misdiagnosed?

Impact of routine clinic measurement of serum C-peptide in people with a clinician-diagnosis of type 1 diabetes - PubMed

Serum C-peptide testing can easily be incorporated into an out-patient clinic setting and could be a cost-effective intervention. C-peptide testing should be strongly considered in individuals with a clinician-diagnosis of type 1 diabetes of at least 3 years duration.

pubmed.ncbi.nlm.nih.gov

In the Scottish one though 13% had C-peptide ≥200 pmol/L only half of those got a T1 msdiagnosis, so presumably the rest were T1s still producing (some) insulin....

 

[Marie 2]

Joslyn did some research on continued production of insulin in long term Type 1's. They briefly mention it on this page, hit the plus sign under results and it talks about it.

https://joslin.org/research/medalist-program-study