Thanks for keeping us updated with your Journey CherryAA.
Fat is possibly more important when you are on a fasting regime than most believe. Not only does is slow the carb/insulin
reactions it assists in the replacing of the old cells you will be loosing while in a fasted /Keto state.
I will post a link to an interesting interview Valter Longo being interviewed by Dr Rhonda Patrick it is long at over 1 hour but
some Top information is spread within.
In this conversation, Rhonda and Valter discuss...
• The effects of prolonged fasting, which refers to 2-3 day fasting intervals in mice and 4-5 days in humans.
• Dr. Longo’s work on the fasting-mimicking diet, which is 5 day restricted diet that is meant to simulate some of the biological effects of prolonged fasting while still allowing some food.
• How clinical trials have demonstrated efficacy for this diet for type 2 diabetes, multiple sclerosis, and cancer patients.
• Fasting as an inducer of differential stress resistance, where it can simultaneously make cancer cells more sensitive to death while also making healthy cells more resistant to these same death stimuli (such as chemotherapy) which might otherwise induce cell death amongst healthy cells as collateral damage.
• Fasting as a biological state which humans historically experienced with extreme regularity and we may ultimately need in order to mitigate various disease states.
• The effects of prolonged fasting on the immune system, namely, how it clears away damaged white blood cells via autophagy and how this causes hematopoietic stem cells to self renew and make more stem cells and also produce new blood cells to fully replenish the white blood cell population.
• How prolonged fasting causes a shift in the immune cell population towards one that is more representative of youth by normalizing the ratio of myeloid cells to lymphoid cells.
• The positive effects of prolonged fasting and the fasting-mimicking diet on markers of systemic inflammation, blood glucose levels and other aging biomarkers.
• The conclusions of Dr. Longo & Dr. Marcus Bock’s research comparing 1 week of the fasting-mimicking diet followed by 6 months of mediterranean diet to six months of a ketogenic diet in people with multiple sclerosis.
• The strange, somewhat paradoxical role of autophagy genes in cancer progression and some of the open questions surrounding the exact role that these genes are playing.
• Dr. Longo’s high level thoughts on metformin as an anti-aging drug.
• How the growth hormone/IGF-1 axis is one of the most important genetic pathways in aging from yeast to worms to mice to humans.