Side effects for diabetes drug in head-to-head study

Tue, 05 Dec 2006
A major study has put two diabetes drugs head to head, and drawn some surprising conclusions. Avandia, a newer form of type 2 diabetes drug, was put alongside metformin and glyburide and thoroughly tested. Results indicated that Avandia provided better glucose control but posed a risk of greater side effects, not to mention a higher cost.

The study was conducted at the University of Washington . Glyburide was outperformed by both Avandia and Metformin, leading study author Steven Kahn to say: "People who use glyburide will have to think about changing drugs."

The study was funded by the manufacturer of Avandia, GlaxoSmithKline, and investigated 4, 360 newly diagnosed diabetics . The flipside of the study, that proved the efficiency of Avandia, also revealed that 62 of the patients who took Avandia also developed a heart problem . When compared to the other drugs, 58 patients taking metformin and 41 taking glyburide developed similar heart problems .
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