Diabetes Sufferer and Overweight Can Lead to Kidney Disease

Wed, 09 Nov 2005
If you are a diabetes sufferer and overweight you are at risk of kidney disease.

Kidney disease more likely to develop in overweight and obese people with high blood pressure (hypertension) than in those of ideal body weight, according to the results of a large study.

In the last 20 years, obesity in US adults has doubled from 15% to more than 30%, in so far as now two thirds of US adults are now overweight or obese. Overweight and obesity are known risk factors for several chronic conditions, such as, heart disease, hypertension, and heart disease, but information on risk for chronic kidney disease in overweight and obese individuals is currently limited.

The current study supports "an association between obesity and risk of chronic kidney disease in this high-risk population," lead investigator Dr. Holly Kramer told Reuters Health. "Obesity represents a constellation of risk factors mediated by insulin resistance which we know increases cardiovascular risk."

After 5 years, the incidence of chronic kidney disease was 28% in those of ideal body mass, 31% in those who were overweight and 34% in the obese, the researchers report in the American Journal of Kidney Diseases.

After adjustment for factors including diabetes and blood pressure, both being overweight and being obese were significantly associated with the development of chronic kidney disease.

Given the effect of obesity on heart disease, Kramer concluded, "it shouldn't be surprising that obesity also increases the risk of chronic kidney disease. The propagating epidemic of obesity in the US can only lead to increasing incidence of CKD over the next decade."
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