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Binding resin effective on diabetic mice

A type of resin that binds to and then eliminates bile acid could be effective in treating obesity and type 2 diabetes . According to a new report published in the journal Diabetes, Colestimide is effective amongst mice.
The researchers, who came from the Osaka University Graduate School of Medicine and the Kinki University School of Medicine, examined the effects of the resin on glucose levels in diabetic mice.
The researchers said: “Since bile acid-binding resins have been clinically used as cholesterol-lowering agents, it is reasonable to try this therapy in patients with type 2 diabetes and dyslipidemia, or abnormal levels of blood fats. Since dyslipidemia in patients with type 2 diabetes leads to high mortality, this research provides a message on the beneficial effect of this kind of drug.”
Colestimide had the effect of preventing diet-induced obesity amongst mice, as well as high blood sugar levels. Amongst those mice that were already obese, the resin was successful in reducing problems. In order to determine the effectiveness of the therapy amongst diabetic humans, controlled trials would be needed in the future, the researchers concluded.

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