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Diabetes linked to risk of colorectal adenomas

Researchers have revealed that colorectal adenomas are significantly more common in adults suffering from type 2 diabetes than they are for the general adult population. The study, led by Dr. Nisheet Waghray of the Cleveland MetroHealth Medical Center in the US, monitored 860 patients who were screened for colonoscopy over a three-year period.
It was found that three or more adenomas, adenomas larger than 1 cm, a proximal location of advanced adenomas and a higher than average number of polyps, were significantly more common in diabetes patients than in the non-diabetics . Waghray commented “Colonic adenomas and advanced adenomas were independently predicted by diabetes.”
It was shown that 14 per cent of patients with diabetes had three or more adenomas, compared with 10 per cent in the general population; the rate of adenomas larger than 1 cm was 9.7 per cent against 4.7 per cent, respectively. The research indicated that type 2 diabetes can influence both the amount of adenomatous polyps and their location within the colon.
Although previous studies have found there to be a 30–40 per cent rise in colorectal cancer risk in adults with type 2 diabetes, scientists have not understood how the risk of colorectal adenomas is linked with type 2 diabetes.
The age difference or ethnic background of patients didn’t turn out to be a significant factor, or body mass index, family history, use of tobacco, alcohol or non-steroidal anti-inflammatory drugs .

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