A new study by scientists at the University of North Carolina at Chapel Hill School of Medicine in the US have explored the link between the consumption of a high-fat diet and the risk of type 2 diabetes .
A diet rich in saturated fats is believed to be a key contributor to type 2 diabetes, and patients with the condition have overly active immune responses, which means their bodies contain inflammatory chemicals. The research, which studied response to a high fat diet in mice, revealed that saturated fatty acids can activate immune cells to produce interleukin-1beta, an inflammatory protein .
Jenny Y. Ting, senior co-author on the study, which was published in the journal Nature Immunology, commented “The cellular path that mediates fatty acid metabolism is also the one that causes interleukin-1beta production.”
She added “Interleukin-1beta then acts on tissues and organs such as the liver, muscle and fat (adipose) to turn off their response to insulin, making them insulin resistant. As a result, activation of this pathway by fatty acid can lead to insulin resistance and type 2 diabetes symptoms .”
People with type 2 diabetes can be overweight and have bodies that are resistant to insulin, the hormone that takes sugar from the blood to store it as energy.

Get our free newsletters

Stay up to date with the latest news, research and breakthroughs.

You May Also Like

Type 2 diabetes found to be a ‘significant risk factor’ among stroke victims

More evidence has been published which supports that diabetes is a “significant…

Public Health England considers low carb approach for type 2 diabetes

The low carb approach is being considered by the government to be…

Coronavirus: UK instructed to stay at home this weekend

Health Secretary Matt Hancock has said that staying at home this weekend…