The research, conducted by the University of East Anglia (UEA) and the Norfolk and Norwich University Hospital (NNUH), involved looking at 52 studies which had already investigated health outcomes and coronavirus.
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Initially, experts had expressed concern that some medications administered for high blood pressure could significantly impact people who test positive for COVID-19.
But the UEA team say this is not the case and they ruled it out by focussing on people who take antihypertensives and comparing critical health among them once they test positive for COVID-19.
In fact, they say there is evidence to suggest that these drugs might actually improve COVID-19 survival rates.
Old age and having more than one serious health condition also significantly impacts the health outcome.
Lead researcher Dr Vassilios Vassiliou, from UEA’s Norwich Medical School and Honorary Consultant Cardiologist at NNUH, said: “What a meta-analysis gives us is the really big picture. We looked at the combined findings of 52 separate studies involving over 100,000 patients. It is the most comprehensive study of its kind to date.
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“With these increased numbers, what we can see very clearly now, is that it is the comorbidities such as cardiac disease or respiratory disease, cancer or obesity amongst others that lead to an increased mortality.
“And we can confirm that the blood pressure medications themselves are protective — not only for people who have high blood pressure, but for people with a range of other comorbidities as well.”
The findings have been published in the Journal of the American Medical Association (JAMA) Network Open.