A group of Boston-based academics have recently launched a detailed investigation looking into why exercise impacts individuals in numerous ways.

The findings are outlined in the Nature Metabolism journal and guides people to their most suited fitness activity.

The analysis also distinguishes the healing objectives linked to metabolism related diseases.

Senior researcher Dr Robert E. Gerszten said: “While groups as a whole benefit from exercise, the variability in responses between any two individuals undergoing the very same exercise regimen is actually quite striking. For example, some may experience improved endurance while others will see improved blood sugar levels.”

He added: “To date, no aspects of an individual’s baseline clinical profile allow us to predict beforehand who is most likely to derive a significant cardiorespiratory fitness benefit from exercise training.”

During a 20-week exercise plan, the group of researchers recorded the blood levels of 5,000 proteins in 650 inactive adults at the beginning and end of the experiment.

Academic Dr Jeremy Robbins said: “We were particularly interested at looking at proteins in the blood to study the effects of exercise because there is a growing body of evidence showing that exercise stimulates the secretion of chemicals into circulation that can impart their effects on distant organs.”

Before starting the exercise course, a person’s cardiorespiratory ability, or VO2max, recorded a group of 147 proteins.

After the 20-week fitness plan ended, a group of 102 proteins per person were recorded which illustrated alterations in their VO2max.

Dr Gerszten said: “We identified proteins that emanate from bone, muscle, and blood vessels that are strongly related to cardiorespiratory fitness and had never been previously associated with exercise training responses.”

He added: “Baseline levels of several proteins predicted who would respond to the exercise training protocol far better than any of our established patient factors.”

In a previous research experiment the academics exposed the connection between cardiorespiratory fitness and lasting health implications by finding the risk of dying young being linked to a few of these proteins.

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