Metabolic syndrome has been found to be associated with an increased risk of osteoarthritis, particularly in people with elevated C-reactive protein levels.

The relationship between metabolic syndrome, its components, and the risk of osteoarthritis has been a topic of conflicting evidence in different studies.

Osteoarthritis is a degenerative joint disease, in which the tissues in the joint break down over time.

It is the most common type of arthritis and mainly affects older people.

Metabolic syndrome is the name for a group of health problems that put you at risk of type 2 diabetes or conditions that affect your heart or blood vessels.

More than 300,000 individuals from the UK Biobank were examined as part of the research investigation.

A total of 45,581 cases of osteoarthritis were identified among the participants.

According to the findings, the participants with metabolic syndrome were 15% more at risk of developing osteoarthritis compared to those without the condition.

Additionally, the results show that central obesity was associated with a 58% increased risk of osteoarthritis, while hyperglycaemia was linked to a 13% higher risk.

Dyslipidaemia and high-density lipoprotein were also found to be slightly associated with a higher risk of osteoarthritis, the study has reported.

Furthermore, the presence of metabolic syndrome increased the risk of osteoarthritis by up to 35% in people with elevated C-reactive protein levels.

The authors concluded: “These findings highlight the significance of managing metabolic syndrome as a preventive and intervention measure for osteoarthritis.”

Read the study here.

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