Metabolic syndrome has been found to be associated with an increased risk of osteoarthritis, particularly in people with elevated C-reactive protein levels.
The relationship between metabolic syndrome, its components, and the risk of osteoarthritis has been a topic of conflicting evidence in different studies.
Osteoarthritis is a degenerative joint disease, in which the tissues in the joint break down over time.
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It is the most common type of arthritis and mainly affects older people.
Metabolic syndrome is the name for a group of health problems that put you at risk of type 2 diabetes or conditions that affect your heart or blood vessels.
More than 300,000 individuals from the UK Biobank were examined as part of the research investigation.
A total of 45,581 cases of osteoarthritis were identified among the participants.
According to the findings, the participants with metabolic syndrome were 15% more at risk of developing osteoarthritis compared to those without the condition.
Additionally, the results show that central obesity was associated with a 58% increased risk of osteoarthritis, while hyperglycaemia was linked to a 13% higher risk.
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Dyslipidaemia and high-density lipoprotein were also found to be slightly associated with a higher risk of osteoarthritis, the study has reported.
Furthermore, the presence of metabolic syndrome increased the risk of osteoarthritis by up to 35% in people with elevated C-reactive protein levels.
The authors concluded: “These findings highlight the significance of managing metabolic syndrome as a preventive and intervention measure for osteoarthritis.”
Read the study here.
