The Sanford Project, headquartered in Sioux Fall, South Dakota, has begun clinical trials on people just diagnosed with type 1 diabetes, while a second location for trials has been announced at Sanford Diabetes Center in Fargo. The project, which has the aim of researching and curing type 1 diabetes, is currently recruiting patients for study, particularly those who are between 11 and 45 and have been diagnosed with type 1 diabetes within the last six months.
The drugs under review are sitagliptin (which is sold under the brand name Januvia) and lansoprazole (a proton pump inhibitor ), both of which are commonly used on their own to treat other medical conditions. The former is used for controlling blood sugar levels in patients with type 2 diabetes, while lansoprazole is currently given as an antacid for heartburn .
Alex Rabinovitch, lead research on the trial and associate director of The Sanford Project, commented “The objective of this clinical trial (research study) is to determine if the combination of two medications can rescue the few beta cells that remain soon after the diagnosis of type 1 diabetes; and whether new beta cells can even be regenerated.”
He added “The investigational combinations of these medications could possibly allow patients to decrease or no longer need to inject insulin to keep their blood levels under proper control.”

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