Type 1 Diabetes

Type 1 Diabetes affects the body such that it can no longer produce insulin Type 1 diabetes affects the body such that it can no longer produce insulin

Type 1 diabetes is an autoimmune disease that causes the insulin producing beta cells in the pancreas to be destroyed, preventing the body from being able to produce enough insulin to adequately regulate blood glucose levels.

Type 1 diabetes may sometimes be referred to as juvenile diabetes, however, this term is generally regarded as outdated as, whilst it is commonly diagnosed in children, the condition can develop at any age.

Insulin dependent diabetes is another term that may sometimes be used to describe type 1 diabetes.

Because type 1 diabetes causes the loss of insulin production, it therefore requires regular insulin administration either by injection or by insulin pump.

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Type 1 diabetes symptoms

Type 1 diabetes symptoms should be acted upon immediately, as without treatment this type of diabetes can be deadly.

Symptoms include:

Type 1 diabetes tends to develop more slowly in adults than it does in children and in some cases type 1 diabetes in adults may be misdiagnosed as type 2 diabetes.

Type 1 diabetes in adults over 35 years old will sometimes be referred to as Latent Autoimmune Diabetes of Adulthood (LADA).

Type 1 causes

Type 1 diabetes is caused by a fault in the body’s immune response in which the immune system mistakenly targets and kills beta cells, the cells in the pancreas responsible for producing insulin.

As more insulin producing cells in the pancreas are killed off, the body can no longer control its blood glucose levels and the symptoms of diabetes begin to appear.

What causes the initial fault in the immune system is yet to be discovered, however, research suggests that the condition results from a combination of genetic predisposition with an environmental trigger.

What triggers the immune system to behave this way is yet to be conclusively identified. To date, the strongest evidence points towards a virus as being the most likely trigger.

Diagnosis

If you show signs of having diabetes, your doctor may use blood or urine tests to diagnose diabetes. Your doctor should consider which type of diabetes you have as this can affect how your diabetes is treated. If the type of diabetes is unclear, your doctor may decide to carry out one or more of the following tests:

Because type 1 diabetes can develop quickly within children and young adults, a diagnosis of type 1 diabetes should be followed by same day referral to a multidisciplinary paediatric diabetes care team.

Transcript

Type 1 diabetes is an autoimmune disease that causes the body to kill off its own insulin producing cells. Unlike type 2 diabetes, there exists no link between body size and type 1 diabetes.

Type 1 diabetes usually starts in childhood but can start in adulthood too. Type 1 diabetes can come quickly and symptoms can get stronger by the day. The earlier it’s diagnosed the better. The symptoms of type 1 diabetes are a reaction to the high amount of sugar in the blood.

The body will try to flush out excess sugar through urine which means you will be going to the wee a lot; especially at night, drinking much more than normal, you may also notice itching down below. Less insulin means the sugar in your blood can’t fuel your body cells so you’ll feel tired and lethargic, and may experience rapid weight loss.

If diabetes is left to develop, you may notice you get either blurred vision or start vomiting. If you notice these symptoms act quickly and arrange to see a doctor immediately.

If you have some of the symptoms, arrange to see a doctor who will take a finger prick blood glucose test or possibly a urine test. The doctor may be able to diagnose you there and then.

Type 1 diabetes is treated by taking insulin You will start by taking injections and can either continue taking injections or may move onto being treated by an insulin pump.

You will need to regularly test your blood, with finger prick tests. Injections and blood tests do get easier over time. You will also need to be aware of what you’re eating, particularly how much carbohydrate you’re having.

We don’t know. Research hasn’t been able to give a clear answer to this yet. What we do know is that genetics plays a part and there seems to be a link with vitamin D, although the link is not currently well understood.

A diagnosis of diabetes is not all doom and gloom. With good control you can lead a long and happy life. People with type 1 diabetes have been known to live into their nineties.

One such person is Bob Krause who lived with type 1 diabetes for over 85 years.

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Treatment for type 1 diabetes

The impairment of the pancreas’ ability to produce insulin in type 1 diabetes means that insulin treatment is necessary.

Most people will take insulin by injection with insulin pens. Insulin can also be delivered by wearing an insulin pump. Use of an insulin pump will be considered in people that express an interest in having one and that meet certain eligibility criteria.

It is important that you are given education on how to balance insulin doses with dietary intake and physical activity and how to use blood glucose testing to help you control your diabetes.

Staying physically active and exercising regularly and eating a healthy diet are also important towards maintaining good blood glucose control and minimising the risk of long term diabetes complications. Although diet and exercise have a role to play in type 1 diabetes management, they cannot reverse the disease or eliminate the need for insulin.

Type 1 diabetes and complications

Type 1 diabetes is a serious condition which can carry a significant risk of both short term and long term complications.

Short term complications

Short term complications can occur if blood glucose levels go too low or if insulin injections are missed. The short term complications that can occur are:

  • Hypoglycemia - too low blood sugar levels
  • Ketoacidosis - which can occur if insulin doses are missed or blood glucose levels become too high

Long term complications

Type 1 diabetes can lead to the development of the following long term diabetes complications:

Whilst the list of complications is a scary prospect, the chances of developing these can be significantly reduced by maintaining good control of your blood glucose levels and ensuring you attend all your diabetic complication screening appointments.

Prevention

In future, research may find a way to halt the development of type 1 diabetes but, to date, no intervention has successfully preventing type 1 diabetes in humans.

Type 1 diabetes research

Researchers from around the globe are looking for ways to improve type 1 diabetes treatment and to investigate possible cures. Important research areas include:

Type 1 diabetes facts

The risk of developing type 1 diabetes can be affected by your genetics; i.e. if your parents or siblings have type 1 diabetes.

  • In terms of inheritance of type 1 diabetes - there is a 2% risk if the mother has type 1 diabetes, 8% risk if the father has type 1 diabetes; and a 30% risk of the child developing type 1 diabetes if both parents are type 1 [5]
  • Within 20 years of diagnosis of type 1 diabetes, nearly all of those diagnosed have some degree of retinopathy [1]

There is also a sub-type of type 1 diabetes known as brittle diabetes.

Famous people with type 1 diabetes include: